1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, 2 China National Clinical Research Center for Neurological Diseases, Beijing, China, 3 Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China, 4 Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China, 5 Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China, 6 Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China, 7 Centre for Health and Social Care Improvement, Faculty of Education Health and Wellbeing, University of Wolverhampton, Wolverhampton, United Kingdom, 8 Post Graduate Academic Institute of Medicine, University of Wolverhampton, Wolverhampton, United Kingdom ☯ These authors contributed equally to this work. ‡ These authors also contributed equally to this work. * [email protected] (YJW); [email protected] (YLW); [email protected] (RLC)
Abstract Background To investigate the impact of low socioeconomic status (SES), indicated by low level of education, occupation and income, on 3 months functional outcome after ischemic stroke.
Methods We analyzed data from the China National Stroke Registry (CNSR), a multicenter and prospective registry of consecutive patients with acute cerebrovascular events occurred between September 2007 and August 2008. 11226 patients with ischemic stroke had SES and clinical characteristics data collected at baseline and mRS measured as indicator of functional outcome in 3 months follow up. Multinomial and ordinal logistic regression models were performed to examine associations between SES and the functional outcome.
Results At 3 months after stroke, 5.3% of total patients had mRS scored at 5, 11.3% at score 4, 11.1% at score 3, 14.4% at score 2, 34.2% at score 1 and 23.7% at score 0. Compared to patients with educational level of 6 years and non-manual laboring, those < 6 years and manual laboring tended to have higher mRS score (P
C-reactive protein, a well known marker of inflammation is being investigated as a probable marker of predicting acute cardiovascular events and its severity. The aim of the present study was to assess the possible role of highly-sensitivity C-reacti
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