EXPERIMENTAL AND THERAPEUTIC MEDICINE 7: 1595-1598, 2014

Intraocular lens implantation for patients with coloboma of the iris JUANJUAN LI1, YAN LI2, ZHULIN HU1 and LEI KONG1 1

Department of Ophthalmology, The Fourth Affiliated Hospital of Kunming Medical University; 2 Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650021, P.R. China Received September 23, 2013; Accepted January 30, 2014 DOI: 10.3892/etm.2014.1615

Abstract. The aim of this study was to analyze the techniques for intraocular lens (IOL) implantation in patients with coloboma of the iris. A retrospective cohort study was used to analyze the degree of iris coloboma and the characteristics of the crystalline lens in 56 patients with iris coloboma. The patients with a lesser degree of coloboma of the iris and an intact lens capsule were treated by iris suture and IOL implantation into the posterior chamber. Patients with an iris coloboma confined to one quadrant, severe iris atrophy and significant lens capsule coloboma were treated with an annular suture at the edge of the pupil and IOL implantation into the anterior chamber. Patients with a greater degree of iris coloboma and an intact lens capsule were treated with an artificial iris and IOL implantation. The patients were followed up for between five months and five years after surgery. Data relating to vision, photophobia, IOL location, postoperative complications and treatment were also obtained at follow-up. The vision of the patients was improved to varying degrees following the surgery, with the exception of those with amblyopia or serious corneal scars. The photophobia of the patients had also improved. The patients' levels of satisfaction and comfort were deemed to be satisfactory. Early postoperative complications included hyphema, increased intraocular pressure and uveitis. However, serious complications such as corneal decompensation and IOL dislocation were not observed. Various techniques for IOL implantation were selected based on the degree of iris and lens capsule coloboma; these techniques were capable of improving the vision and photophobia of the patients.

Correspondence to: Dr Yan Li, Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan 650021, P.R. China E-mail: [email protected]

Key words: iris coloboma, crystalline lens, man-made, surgical operation

Introduction The iris has important physiological functions with regard to regulating the amount of light that enters the eyes, increasing focal depth and decreasing eyeball aberrations (1). Patients with apriority, traumatic or surgical aniridia, or serious iris coloboma exhibit several symptoms, including serious photophobia, monodiplopia, glare and unsatisfactory corrected eyesight (2). Due to congenital dysplasia, trauma, surgery, the integrity of the iris is damaged or missing and normal morphology and size of pupil are damaged, referred to as the ‘iris defect’. Furthermore, these patients also present with cataracts and crystalline lens dislocation (3,4). Various surgical techniques may be used to conduct IOL implantation when patients exhibit with iris coloboma and cataracts (5,6). In the present study, a review of patients treated with various surgical techniques based on different iris coloboma and crystalline lens anomalies was carried out, and the results of the various treatments are reported. Materials and methods General data. A total of 56 patients, comprising 38 males and 18 females, with ages ranging from 2.5 to 45.2 years (mean, 21.6±2.4 years), who were treated with IOL implants at The Fourth Affiliated Hospital of Kunming Medical University (Kunming, China) from January 2006 to January 2011 were included in this study. The numbers of patients who required monocular and binocular treatment were 49 and 7, respectively. In total, 49 patients presented with traumatic iris coloboma with cataracts or crystalline lens coloboma and seven presented with congenital iris coloboma and cataracts. The best corrected visual acuity was

Intraocular lens implantation for patients with coloboma of the iris.

The aim of this study was to analyze the techniques for intraocular lens (IOL) implantation in patients with coloboma of the iris. A retrospective coh...
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