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Case Reports
Intracranial Tuberculoma Developing During Therapy for Tuberculous Meningitis LCDR JOSEPH L. MALONE, MC, USN San Diego LCDR SCOTT PAPARELLO, MC, USN LCDR LELAND S. RICKMAN, MC, USN CAPT KENNETH F WAGNER, MC, USN LT BRIAN MONAHAN, MC, USN Bethesda, Maryland CAPT EDWARD C. OLDFIELD, MC, USN San Diego on ten patients in during the treatdeveloped whom intracranial tuberculomas ment of tuberculosis. Others have reported a 4.5 % to 28 % incidence of intracranial tuberculomas complicating tuberculous meningitis.2 3 We report an additional such case.
'fOH AND CO-WORKERS recently reported
Report of a Case The patient, a 39-year-old Filipino-American man, was admitted to hospital because of nausea, fevers, and headaches for two weeks. He had grown up in the Philippines and joined the United States military 18 years before admission. A greater than 10 mm reaction to a tuberculin purified protein derivative (PPD) skin test was noted, and his chest radiograph was normal at the time of entry into military service. He never received isoniazid prophylaxis; subsequently, he was not known to have any abnormal findings on chest radiographs. He said he had no risk factors for infection with the human immunodeficiency virus (HIV). He did not have diabetes mellitus, was taking no medications, and had no other known medical problems at the time of presentation. The results of a physical examination and a contrast-enhanced computed tomographic (CT) scan of the head were normal. An initial cerebrospinal fluid (CSF) analysis revealed the following: total protein, 1.02 grams per liter (102 mg per dl [normal,
Case Reports
Intracranial Tuberculoma Developing During Therapy for Tuberculous Meningitis LCDR JOSEPH L. MALONE, MC, USN San Diego LCDR SCOTT PAPARELLO, MC, USN LCDR LELAND S. RICKMAN, MC, USN CAPT KENNETH F WAGNER, MC, USN LT BRIAN MONAHAN, MC, USN Bethesda, Maryland CAPT EDWARD C. OLDFIELD, MC, USN San Diego on ten patients in during the treatdeveloped whom intracranial tuberculomas ment of tuberculosis. Others have reported a 4.5 % to 28 % incidence of intracranial tuberculomas complicating tuberculous meningitis.2 3 We report an additional such case.
'fOH AND CO-WORKERS recently reported
Report of a Case The patient, a 39-year-old Filipino-American man, was admitted to hospital because of nausea, fevers, and headaches for two weeks. He had grown up in the Philippines and joined the United States military 18 years before admission. A greater than 10 mm reaction to a tuberculin purified protein derivative (PPD) skin test was noted, and his chest radiograph was normal at the time of entry into military service. He never received isoniazid prophylaxis; subsequently, he was not known to have any abnormal findings on chest radiographs. He said he had no risk factors for infection with the human immunodeficiency virus (HIV). He did not have diabetes mellitus, was taking no medications, and had no other known medical problems at the time of presentation. The results of a physical examination and a contrast-enhanced computed tomographic (CT) scan of the head were normal. An initial cerebrospinal fluid (CSF) analysis revealed the following: total protein, 1.02 grams per liter (102 mg per dl [normal,
