International Journal of Urology (2015)

doi: 10.1111/iju.12681

Original Article

International Prostate Symptom Score is a predictive factor of lower urinary tract symptoms after radical prostatectomy Younes Bayoud,1 Alexandre de la Taille,1 Adil Ouzzane,1 Guillaume Ploussard,1 Yves Allory,2 René Yiou,1 Dimitri Vordos,1 Andras Hoznek1 and Laurent Salomon1 Departments of 1Urology and 2Pathology, APHP, CHU Henri Mondor, Créteil, France Abbreviations & Acronyms AUA = American Urological Association BMI = body mass index BPH = benign prostatic hyperplasia EBRT = external beam radiotherapy IPSS = International Prostate Symptom Score LUTS = lower urinary tract symptoms PCa = prostate cancer PSA = prostate-specific antigen QoL = quality of life RP = radical prostatectomy RPP = radical perineal prostatectomy RRP = retropubic prostatectomy Correspondence: Younes Bayoud, M.D., Department of Urology, APHP, CHU Henri Mondor, 32 rue de chaligny, 75012 Paris, France. Email: [email protected] Received 2 April 2014; accepted 28 October 2014.

Objective: To evaluate the impact of radical prostatectomy on lower urinary tract symptoms by using the International Prostate Symptom Score and International Prostate Symptom Score quality of life. Methods: The present prospective study comprised 804 patients having localized prostate cancer who underwent radical prostatectomy. International Prostate Symptom Score and International Prostate Symptom Score quality of life were recorded preoperatively, and at 1, 3, 6, 12 and 24 months. Two study groups were considered: group 1 included patients with International Prostate Symptom Score 7 (mild) and group 2 included patients with International Prostate Symptom Score 8 (moderate to severe). Student’s t-test and logistic regression were carried out to detect a predictive factor of International Prostate Symptom Score 7 at 24 months. Results: The mean International Prostate Symptom Score was 5.58 ± 6.6, 11.12 ± 7.1 and 7.62 ± 6 at baseline, 1 month and 3 months, respectively (P