Oncotarget, Vol. 7, No. 38
www.impactjournals.com/oncotarget/
Research Paper
Initial intracranial pressure as a prognosticator in head-injured patients undergoing decompressive craniectomy Hua Liu1,*, Rong Xu2,*, Jian Yang1, Guanghui Ren1, Shengxue He3 1
Department of Neurosurgery, The First People’s Hospital of Kunshan Affiliated with Jiangsu University, Suzhou, Jiangsu, China
2
Department of Pediatric Surgery, The First People’s Hospital of Kunshan Affiliated with Jiangsu University, Suzhou, Jiangsu, China
3
Department of Neurosurgery, The Affiliated Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
*
These authors have contributed equally to this work
Correspondence to: Shengxue He, email: [email protected] Keywords: initial intracranial pressure, traumatic brain injury, decompressive craniectomy Received: June 06, 2016 Accepted: August 15, 2016 Published: August 26, 2016
ABSTRACT Purpose: To examine the prognostic discrimination and prediction of initial intracranial pressure (ICP) in patients with traumatic brain injury (TBI) undergoing decompressive craniectomy (DC). Results: The relationship between the initial ICP value and prognosis was quantified, and higher values indicated worse patient outcomes. Univariate analysis showed that the initial ICP value was significantly associated with mortality (odds ratio: 1.272, 95% confidence interval: 1.116-1.449; P
www.impactjournals.com/oncotarget/
Research Paper
Initial intracranial pressure as a prognosticator in head-injured patients undergoing decompressive craniectomy Hua Liu1,*, Rong Xu2,*, Jian Yang1, Guanghui Ren1, Shengxue He3 1
Department of Neurosurgery, The First People’s Hospital of Kunshan Affiliated with Jiangsu University, Suzhou, Jiangsu, China
2
Department of Pediatric Surgery, The First People’s Hospital of Kunshan Affiliated with Jiangsu University, Suzhou, Jiangsu, China
3
Department of Neurosurgery, The Affiliated Brain Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
*
These authors have contributed equally to this work
Correspondence to: Shengxue He, email: [email protected] Keywords: initial intracranial pressure, traumatic brain injury, decompressive craniectomy Received: June 06, 2016 Accepted: August 15, 2016 Published: August 26, 2016
ABSTRACT Purpose: To examine the prognostic discrimination and prediction of initial intracranial pressure (ICP) in patients with traumatic brain injury (TBI) undergoing decompressive craniectomy (DC). Results: The relationship between the initial ICP value and prognosis was quantified, and higher values indicated worse patient outcomes. Univariate analysis showed that the initial ICP value was significantly associated with mortality (odds ratio: 1.272, 95% confidence interval: 1.116-1.449; P
