SHORT

INHIBITIONS

COMMUNICATIONS

BY COLCHICINE,

CHALASIN-B

OF

THE

CYTOPLASMIC RELEASE

OKA,

VINBLASTINE

STIMULATORY ON

ADRENOM

EDULLARY

Takeshi

AND

EFFECT

FRACTION

FROM

Motoo

Japan. J. Pharmacol. 25, 79 (1975)

CYTO

OF

THE

CATECHOLAMINE

KASHIMOTO

GRANULES

and l=utoshi IZUMI

Department of Pharmacology II, Osaka University School of .1ledicinc, Osaka, Japan Accepted October

Microtubules hormones

and microfilaments

and amines,

which

disrupt

mones

or amines

from gland

adrenal

blastine

or cytochalasin-B

adrenal

release from

stimulatory

the cytoplasmic (18).

fraction

Results arc summarised

vin

that

medulla

ATP. Mg"

release, using

the release

of

catechol

of Ca"

(supernatant stimulated

(