EXPERIMENTAL AND THERAPEUTIC MEDICINE 14: 913-916, 2017

Influence of nutritional intervention on children with type 1 diabetes mellitus and DPP-4 in serum YAN-JUN DONG1, LI-JUAN LIU1, HUI-MING CHEN2, JING SUN2, MING-HUA XIAO2 and JIN-HUI WU2 1

Department of Laboratory Medicine, People's Hospital of Rizhao, Rizhao, Shandong 261000; 2Department of Clinical Nutrition, Guangzhou Women and Children's Medical Center, Guangzhou, Guangdong 510623, P.R. China Received September 21, 2016; Accepted January 16, 2017 DOI: 10.3892/etm.2017.4575

Abstract. The level of dipeptidyl peptidase-4 (DPP-4) of children with type 1 diabetes mellitus (T1DM) was observed to evaluate the improvement in function of the nutritional intervention. In total, 132 children with T1DM (T1DM group) and 132 healthy children (NC group) based on physical examination admitted to our hospital from September 2014 to June 2015 and were studied. General data of the two groups as well as the concentration of DPP-4 and various biochemical criterion in peripheral serum were collected and analyzed. Compared with NC group, DPP-4 level of T1DM group was obviously increased (P0.05 0.581 0.10 0.642 0.652 >0.05 0.768 0.08 0.871 0.981