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Original Article

DOI: 10.4103/2229-5151.124117 Quick Response Code:

Influence of non‑surgical risk factors on anastomotic leakage after major gastrointestinal surgery: Audit from a tertiary care teaching institute Anirban Hom Choudhuri, Rajeev Uppal, Mritunjay Kumar

ABSTRACT Context: The occurence of anastomotic leakage after gastointestinal resection and anastomosis is associated with significant mortality and morbidity. Aims: There is dearth of evidence in the literature on the influence of various non‑surgical factors in causing anastomotic leakage although many studies have identified their possible role. Materials and Methods: A retrospective audit of all the anastomotic leakages occurring between September 2009 and April 2012 in our institute was performed to identify the potential non‑surgical factors that can influence anastomotic leakage. A total of 137 out of 1246 patients who developed anastmotic leak were analyzed. All the potential non‑surgical causes of anastomotic leakage available in the literature were analyzed by univariate analysis and stepwise multiple logistic regression analysis was done after adjusting for the type of surgery. An intergroup comparison among the patients based on the type of surgery was also performed.

Department of Anesthesiology and Intensive Care, GB Pant Hospital, New Delhi, India Address for correspondence: Dr. Anirban Hom Choudhuri, 2/203, East End Apartments, Mayur Vihar I (extn), Delhi ‑ 110 096, India. E‑mail: [email protected]

Results: The following factors were found to be independently associated with increased risk of anastomotic leak: (1) albumin

Influence of non-surgical risk factors on anastomotic leakage after major gastrointestinal surgery: Audit from a tertiary care teaching institute.

The occurence of anastomotic leakage after gastointestinal resection and anastomosis is associated with significant mortality and morbidity...
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