Original Article

Infectious Disease Markers in Blood Donors Lt Col A Chattoraj*, Col R Behl+, Brig VK Kataria# Abstract Background: The infectious disease markers for which blood donors are screened include anti-human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg), anti-hepatitis C virus (HCV), rapid plasma reagin (RPR) card test for syphilis and malarial parasites. Methods: A total of 6751 donors were screened over three years to assess the prevalence of infectious disease markers. Screening for anti-HIV I and II, HBsAg and anti-HCV was carried out by enzyme linked immunosorbent assay (ELISA). Syphilis was tested using RPR card test. Malarial parasite was tested by detection of genus specific plasmodium lactate dehydrogenase. Result: The overall seropositivity for anti-HIV I and II was nine (0.13%), for HBsAg 67 (0.99%), for anti-HCV 13 (0.19%) and for syphilis 42 (0.62%). No sample showed malarial parasites. There was no significant difference (p>0.05) in the seropositivity of various markers between voluntary and replacement donors. There was a significant decline (p0.05). There is no significant change in the prevalence of HIV positivity over the three year period (Table 2). HBsAg seropositivity ranged from 0.79% in 2003, 1.13%

Classified Specialist (Pathology), +Commanding Officer, Transfusion Centre (Eastern Command), Kolkata. #Commandant, Military Hospital, Dehradun.

*

Received : 19.07.2006; Accepted : 19.03.2007

Email : [email protected]

34

Chattoraj, Behl and Kataria

in 2004 and 1.08% in 2005, the overall figure being 0.99%. There is no significant difference in the prevalence of HBsAg positivity in voluntary and replacement donors (Table 3). There was no significant change in the prevalence of HBsAg over the study period (Table 4). HCV seropositivity fell from 0.41% in 2003 to 0.05% in 2005 with an overall positivity of 0.19%. The difference in prevalence of anti-HCV positivity in voluntary and replacement donors is not significant (Table 5). There was a significant decline (p

Infectious Disease Markers in Blood Donors.

The infectious disease markers for which blood donors are screened include anti-human immunodeficiency virus (HIV), hepatitis B surface antigen (HBsAg...
138KB Sizes 1 Downloads 9 Views