Oral Oncology 51 (2015) e4
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Oral Oncology journal homepage: www.elsevier.com/locate/oraloncology
Letter to the Editor Oral squamous cell disorders/individuals
Conﬂict of interest None declared.
We read with the great interest the article by Mane  on ‘Oral potentially malignant disorder/individual’. The discussion on individuals without any disorders in the oral cavity but prone for oral squamous cell carcinoma (OSCC) transformation is quite conceivable. In our recent attempt to redeﬁne oral potentially malignant disorders (OPMD), we elaborated on the facet of malignant transformation of clinically and histopathologically normal epithelium . Besides, a recently published classiﬁcation on OPMD describes about category where there are no clinically evident lesions in the oral cavity but individuals are prone for OSCC transformation . Therefore, as suggested by the author, it appears quite appropriate to integrate the word ‘individual’ with the terminology ‘OPMD’. However, author’s proposed terminology ‘Oral potentially malignant disorder/individual’ semantically does not support the viewpoint of aforementioned concept. It conveys misapprehension that ‘individuals’ are potentially malignant. Instead, conceptually it means ‘individuals’ are prone for OSCC. OPMD and allied proposed terminologies (precancer, premalignant, preneoplastic, carcinoma prone, epithelial precursor, intraepithelial neoplasia, intra-epithelial carcinoma) are eventually concerns with malignant transformation to OSCC. With this interpretation in mind, we lexicographically and semantically studied different terminologies used for OPMD in the literature. After critical analysis (closeness and/or deviation from the anticipated meaning of ‘OSCC transformation’) of each terminology, we came up with term called ‘OSCC prone disorders’ [4,5]. We strongly believe that there lies sensibility in inclusion of word ‘individual’ in the terminology but its use in conjunction with OPMD conveys the wrong impression. However, our proposed terminology (OSCC prone disorder) is appropriately suited for the inclusion of word ‘individual’ i.e. OSCC prone disorders/individuals. This amendment will bring many entities that harness potential for malignant transformation under one roof. It will direct private dental practioners and public heath dentists in identifying high risk individuals and eventually in early detection of oral cancer. We could like to declare that the modiﬁed terminology is based on the authors’ opinions with the hope of further suggestions from readers.
DOI of original article: http://dx.doi.org/10.1016/j.oraloncology. 2013.10.021
http://dx.doi.org/10.1016/j.oraloncology.2014.09.017 1368-8375/Ó 2014 Elsevier Ltd. All rights reserved.
Funding None declared. References  Manne RK. Oral potentially malignant disorders/individuals. Oral Oncol 2014;50:e7–8.  Sarode SC, Sarode GS, Tupkari JV. Oral potentially malignant disorders: precising the deﬁnition. Oral Oncol 2012;48:759–60.  Sarode SC, Sarode GS, Karmarkar S, Tupkari JV. A new classiﬁcation for potentially malignant disorders of the oral cavity. Oral Oncol 2011;47:920–1.  Sarode SC, Sarode GS, Tupkari JV. Oral potentially malignant disorders: a proposal for terminology and deﬁnition with review of literature. J Oral Maxillofac Pathol 2014;18:77–80.  Sarode SC, Sarode GS, Karmarkar S, Tupkari JV. Oral (mucosal) potentially malignant disorders. Oral Oncol 2012;48:e35–6.
Sachin C. Sarode The Ohio State University, College of Dentistry, Oral Pathology, Columbus, OH, USA Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Maheshnagar, Pimpri, Pune 411018, Maharashtra, India Tel.: +91 9922491465. E-mail address: [email protected]
Gargi S. Sarode Department of Oral Pathology and Microbiology, Dr. D. Y. Patil Dental College and Hospital, Maheshnagar, Pimpri, Pune 411018, Maharashtra, India Tel.: +91 9823871462. E-mail addresses: [email protected]
Available online 24 October 2014