RESEARCH ARTICLE
Independent Association of Circulating Vitamin D Metabolites with Anemia Risk in Patients Scheduled for Cardiac Surgery Jana B. Ernst1☯, Tobias Becker1‡, Joachim Kuhn2‡, Jan F. Gummert1‡, Armin Zittermann1☯* 1 Clinic for Thoracic and Cardiovascular Surgery Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany, 2 Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany ☯ These authors contributed equally to this work. ‡ These authors also contributed equally to this work. * [email protected]
a11111
Abstract Background
OPEN ACCESS Citation: Ernst JB, Becker T, Kuhn J, Gummert JF, Zittermann A (2015) Independent Association of Circulating Vitamin D Metabolites with Anemia Risk in Patients Scheduled for Cardiac Surgery. PLoS ONE 10(4): e0124751. doi:10.1371/journal.pone.0124751 Academic Editor: Andrzej T Slominski, University of Tennessee, UNITED STATES
Preoperative anemia is considered an independent risk factor of poor clinical outcome in cardiac surgical patients. Low vitamin D status may increase anemia risk.
Methods We investigated 3,615 consecutive patients scheduled for cardiac surgery to determine the association between preoperative anemia (hemoglobin [Hb]
Independent Association of Circulating Vitamin D Metabolites with Anemia Risk in Patients Scheduled for Cardiac Surgery Jana B. Ernst1☯, Tobias Becker1‡, Joachim Kuhn2‡, Jan F. Gummert1‡, Armin Zittermann1☯* 1 Clinic for Thoracic and Cardiovascular Surgery Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany, 2 Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany ☯ These authors contributed equally to this work. ‡ These authors also contributed equally to this work. * [email protected]
a11111
Abstract Background
OPEN ACCESS Citation: Ernst JB, Becker T, Kuhn J, Gummert JF, Zittermann A (2015) Independent Association of Circulating Vitamin D Metabolites with Anemia Risk in Patients Scheduled for Cardiac Surgery. PLoS ONE 10(4): e0124751. doi:10.1371/journal.pone.0124751 Academic Editor: Andrzej T Slominski, University of Tennessee, UNITED STATES
Preoperative anemia is considered an independent risk factor of poor clinical outcome in cardiac surgical patients. Low vitamin D status may increase anemia risk.
Methods We investigated 3,615 consecutive patients scheduled for cardiac surgery to determine the association between preoperative anemia (hemoglobin [Hb]
