Accepted Manuscript Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis Anderson Alves de Camargo, PT, MSc Tatiane Soares Amaral, PT Samia Zahi Rached, MD Rodrigo Abensur Athanazio, MD Fernanda de Cordoba Lanza, PT, PhD Luciana Maria Malosa Sampaio, PT, PhD Celso Ricardo Fernandes de Carvalho, PT, PhD Alberto Cukier, MD, PhD Rafael Stelmach, MD, PhD Simone Dal Corso, PT, PhD PII:

S0003-9993(13)01239-2

DOI:

10.1016/j.apmr.2013.11.019

Reference:

YAPMR 55684

To appear in:

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Received Date: 19 June 2013 Revised Date:

5 November 2013

Accepted Date: 25 November 2013

Please cite this article as: Alves de Camargo A, Amaral TS, Rached SZ, Athanazio RA, de Cordoba Lanza F, Malosa Sampaio LM, Fernandes de Carvalho CR, Cukier A, Stelmach R, Corso SD, Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis, ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2014), doi: 10.1016/j.apmr.2013.11.019. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

ACCEPTED MANUSCRIPT

Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis

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Running title: Incremental shuttle walking test and bronchiectasis

Anderson Alves de Camargo1, PT, MSc, Tatiane Soares Amaral1, PT, Samia Zahi Rached2, MD, Rodrigo Abensur Athanazio2, MD, Fernanda de Cordoba Lanza1, PT,

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PhD, Luciana Maria Malosa Sampaio1, PT, PhD, Celso Ricardo Fernandes de

Dal Corso1, PT, PhD

Affiliations

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Carvalho3, PT, PhD, Alberto Cukier2, MD, PhD, Rafael Stelmach2, MD, PhD, Simone

1- Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho -

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UNINOVE, São Paulo, Brazil

2- Pulmonary Division, Heart Insitute (InCor) - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (SP), São Paulo, Brasil

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Brazil

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3- Physiotherapy Department, Faculty of Medicine, University of São Paulo, São Paulo,

Corresponding author: Simone Dal Corso Rua Vergueiro, 235/249 – 2o subsolo Zip code: 01504-001 Sao Paulo, Brazil Phone: 55 11 3385-9226 e-mail: [email protected]

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All authors have no conflicts of interest to disclose regarding this paper.

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INCREMENTAL SHUTTLE WALKING TEST: A REPRODUCIBLE AND VALID

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TEST TO EVALUATE EXERCISE TOLERANCE IN ADULTS WITH NON-

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CYSTIC FIBROSIS BRONCHIECTASIS

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Running title: Incremental shuttle walking test and bronchiectasis

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ABSTRACT

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Objective: To analyze the reliability, validity, and the determinants of the incremental shuttle

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walk test (ISWT) in adults with non-cystic fibrosis bronchiectasis.

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Design: Cross-sectional study

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Setting: Outpatient clinic from a tertiary university hospital

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Participants: Seventy-five subjects (26 male) underwent, on different days, the

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cardiopulmonary exercise testing (CPET) and two ISWTs, 30 min apart. Number of

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steps (steps/day) in daily life was recorded. Concurrent validity was tested by the

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relationship between distance walked with peak load, and oxygen uptake (VO2).

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Interventions: None

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Main Outcome Measures: Distance walked (meters) was compared between the first and

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second ISWT; the greatest distance walked was correlated with peak load and VO2 obtained

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from CPET, steps/day, and dyspnea evaluated by the Medical Research Council (MRC) scale;

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desaturation was compared between CPET and ISWT.

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Results: Distance walked was equivalent between the ISWT-1 (441±152 m) and ISWT-

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2 (445±153 m) with an excellent intraclass correlation coefficient (0.995 [95% CI:

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0.990-0.997]). There were significant correlations between distance walked and peak

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load (r =0.82), VO2 (r =0.72), steps/day (r =0.61), and MRC (r =-0.69). Age, body mass

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index, gender, forced vital capacity (%predicted), dyspnea, and steps/day explained

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70% of the variation in distance walked as expressed in meters and 60% when

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expressed as %predicted. Higher desaturation was observed during ISWT (-4±4%) than

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cycling (-2±3) (p

Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with noncystic fibrosis bronchiectasis.

To analyze the reliability, validity, and determinants of the incremental shuttle walk test (ISWT) in adults with noncystic fibrosis bronchiectasis...
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