Accepted Manuscript Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis Anderson Alves de Camargo, PT, MSc Tatiane Soares Amaral, PT Samia Zahi Rached, MD Rodrigo Abensur Athanazio, MD Fernanda de Cordoba Lanza, PT, PhD Luciana Maria Malosa Sampaio, PT, PhD Celso Ricardo Fernandes de Carvalho, PT, PhD Alberto Cukier, MD, PhD Rafael Stelmach, MD, PhD Simone Dal Corso, PT, PhD PII:
S0003-9993(13)01239-2
DOI:
10.1016/j.apmr.2013.11.019
Reference:
YAPMR 55684
To appear in:
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
Received Date: 19 June 2013 Revised Date:
5 November 2013
Accepted Date: 25 November 2013
Please cite this article as: Alves de Camargo A, Amaral TS, Rached SZ, Athanazio RA, de Cordoba Lanza F, Malosa Sampaio LM, Fernandes de Carvalho CR, Cukier A, Stelmach R, Corso SD, Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis, ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2014), doi: 10.1016/j.apmr.2013.11.019. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Incremental shuttle walking test: a reproducible and valid test to evaluate exercise tolerance in adults with non-cystic fibrosis bronchiectasis
RI PT
Running title: Incremental shuttle walking test and bronchiectasis
Anderson Alves de Camargo1, PT, MSc, Tatiane Soares Amaral1, PT, Samia Zahi Rached2, MD, Rodrigo Abensur Athanazio2, MD, Fernanda de Cordoba Lanza1, PT,
SC
PhD, Luciana Maria Malosa Sampaio1, PT, PhD, Celso Ricardo Fernandes de
Dal Corso1, PT, PhD
Affiliations
M AN U
Carvalho3, PT, PhD, Alberto Cukier2, MD, PhD, Rafael Stelmach2, MD, PhD, Simone
1- Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho -
TE D
UNINOVE, São Paulo, Brazil
2- Pulmonary Division, Heart Insitute (InCor) - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (SP), São Paulo, Brasil
AC C
Brazil
EP
3- Physiotherapy Department, Faculty of Medicine, University of São Paulo, São Paulo,
Corresponding author: Simone Dal Corso Rua Vergueiro, 235/249 – 2o subsolo Zip code: 01504-001 Sao Paulo, Brazil Phone: 55 11 3385-9226 e-mail:
[email protected] ACCEPTED MANUSCRIPT
AC C
EP
TE D
M AN U
SC
RI PT
All authors have no conflicts of interest to disclose regarding this paper.
ACCEPTED MANUSCRIPT 1
1
INCREMENTAL SHUTTLE WALKING TEST: A REPRODUCIBLE AND VALID
2
TEST TO EVALUATE EXERCISE TOLERANCE IN ADULTS WITH NON-
3
CYSTIC FIBROSIS BRONCHIECTASIS
5
Running title: Incremental shuttle walking test and bronchiectasis
6
8
SC
7
RI PT
4
ABSTRACT
10
M AN U
9
Objective: To analyze the reliability, validity, and the determinants of the incremental shuttle
12
walk test (ISWT) in adults with non-cystic fibrosis bronchiectasis.
13
Design: Cross-sectional study
14
Setting: Outpatient clinic from a tertiary university hospital
15
Participants: Seventy-five subjects (26 male) underwent, on different days, the
16
cardiopulmonary exercise testing (CPET) and two ISWTs, 30 min apart. Number of
17
steps (steps/day) in daily life was recorded. Concurrent validity was tested by the
18
relationship between distance walked with peak load, and oxygen uptake (VO2).
19
Interventions: None
20
Main Outcome Measures: Distance walked (meters) was compared between the first and
21
second ISWT; the greatest distance walked was correlated with peak load and VO2 obtained
22
from CPET, steps/day, and dyspnea evaluated by the Medical Research Council (MRC) scale;
23
desaturation was compared between CPET and ISWT.
24
Results: Distance walked was equivalent between the ISWT-1 (441±152 m) and ISWT-
25
2 (445±153 m) with an excellent intraclass correlation coefficient (0.995 [95% CI:
26
0.990-0.997]). There were significant correlations between distance walked and peak
AC C
EP
TE D
11
ACCEPTED MANUSCRIPT 2
load (r =0.82), VO2 (r =0.72), steps/day (r =0.61), and MRC (r =-0.69). Age, body mass
28
index, gender, forced vital capacity (%predicted), dyspnea, and steps/day explained
29
70% of the variation in distance walked as expressed in meters and 60% when
30
expressed as %predicted. Higher desaturation was observed during ISWT (-4±4%) than
31
cycling (-2±3) (p