Journal of Antimicrobial Chemotherapy (1979) 5, 413-418
In vitro susceptibility of urinary isolates of Escherichia coti to cinoxacin
M. Barnham* and H. Gay a
Two hundred and fifty-four urinary isolates of Escherichia coli were tested for susceptibility to cinoxacin and nalidixic acid by disc diffusion and plate dilution methods. All the isolates tested were susceptible to both drugs. The mean minimal inhibitory concentration (MIC) of cinoxacin was significantly lower for these strains than that of nalidixic acid. Introduction Cinoxacin (Compound 64716, Lilly) is a synthetic antibacterial agent chemically similar to nalidixic and oxolinic acids. Its spectrum of activity resembles that of nalidixic acid and includes the majority of Gram-negative urinary pathogens (Wick, Preston, White
In vitro susceptibility of urinary isolates of Escherichia coti to cinoxacin
M. Barnham* and H. Gay a
Two hundred and fifty-four urinary isolates of Escherichia coli were tested for susceptibility to cinoxacin and nalidixic acid by disc diffusion and plate dilution methods. All the isolates tested were susceptible to both drugs. The mean minimal inhibitory concentration (MIC) of cinoxacin was significantly lower for these strains than that of nalidixic acid. Introduction Cinoxacin (Compound 64716, Lilly) is a synthetic antibacterial agent chemically similar to nalidixic and oxolinic acids. Its spectrum of activity resembles that of nalidixic acid and includes the majority of Gram-negative urinary pathogens (Wick, Preston, White
