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Int J Drug Policy. Author manuscript; available in PMC 2017 April 01. Published in final edited form as: Int J Drug Policy. 2016 April ; 30: 74–81. doi:10.1016/j.drugpo.2016.03.005.
Improvements in Health-related Quality of Life among Methadone Maintenance Clients in Dar es Salaam, Tanzania Omary Ubuguyu, MD, Mmeda, Olivia C. Tran, MPHb, R. Douglas Bruce, MD, MA, MScc, Frank Masao, MD, Mmeda, Cassian Nyandindi, MD, Mmeda, Norman Sabuni, MDd, Sheryl McCurdy, PhDe, Jessie Mbwambo, MDa, and Barrot H. Lambdin, PhD, MPHf,g,h
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Omary Ubuguyu:
[email protected]; Olivia C. Tran:
[email protected]; R. Douglas Bruce:
[email protected]; Frank Masao:
[email protected]; Cassian Nyandindi:
[email protected]; Norman Sabuni:
[email protected]; Sheryl McCurdy:
[email protected]; Jessie Mbwambo:
[email protected]; Barrot H. Lambdin:
[email protected] aMuhimbili bPangaea cYale
University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania Global AIDS, 436 14th St, Suite 920, Oakland, CA 94612
University, New Haven, CT 06520
dTanzania
Ministry of Health and Social Welfare, 6 Samora Machel Ave, Dar es Salaam, Tanzania
eUniversity
of Texas School of Public Health, 7000 Fannin St, Houston, TX, USA
fRTI-International, gDepartment
351 California St, Suite 500, San Francisco, CA 94104
of Global Health, University of Washington, Seatttle, WA, USA
Author Manuscript
hDepartment
of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA, (415) 848-1334
Abstract Background—Injection of heroin has become widespread in Dar es Salaam, Tanzania and is spreading throughout the country. To prevent potential bridging of HIV epidemics, the Tanzanian government established a methadone maintenance treatment (MMT) clinic in February 2011. We assess the effect of MMT on health-related quality of life (HRQOL) and examine factors, particularly HIV infection and methadone dose, associated with changes in HRQOL.
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Methods—This study utilized routine data on clients enrolling in methadone from February 2011 to April 2012 at Muhimbili National Hospital. Change in physical (PCS) and mental health (MCS) composite scores, as measured by the SF-12 tool, were the primary outcomes. Backward stepwise linear regression, with a criterion of p