Improvement in estimated glomerular filtration rate in patients with chronic kidney disease undergoing catheter ablation for atrial fibrillation

Short Title: AF ablation and eGFR

Leenhapong Navaravong, M.D., Michel Barakat, M.D., Nathan Burgon, B.S., Christian Mahnkopf, M.D., Matthias Koopmann, M.D., Ravi Ranjan, M.D., Ph.D., Eugene Kholmovski, Ph.D., Nassir Marrouche, M.D., Nazem Akoum, M.D., M.S. From the Comprehensive Arrhythmia Research and Management (CARMA) Center, University of Utah Division of Cardiovascular Medicine

Corresponding Author: Nazem Akoum, MD 50 North Medical Drive, Salt Lake City, UT 84132 Email: [email protected] Phone: 801-213-2387 Fax: 801-581-7735

N. Marrouche reports stock holdings in Marrek, Inc. Other authors: No disclosures.

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/jce.12530. This article is protected by copyright. All rights reserved.

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Abstract:

Introduction: Chronic kidney disease (CKD) and atrial fibrillation (AF) often co-exist. We studied the association of CKD with atrial fibrosis and the effect of AF ablation on kidney function. Methods: AF Patients who had a pre- and post-ablation serum creatinine and who completed a late gadolinium enhancement cardiac MRI (LGE-MRI) prior to ablation were included. Estimated Glomerular Filtration Rate (eGFR) was calculated and CKD was staged using the National Kidney Foundation guidelines. Patient with eGFR

Improvement in estimated glomerular filtration rate in patients with chronic kidney disease undergoing catheter ablation for atrial fibrillation.

Chronic kidney disease (CKD) and atrial fibrillation (AF) often coexist. We studied the association of CKD with atrial fibrosis and the effect of AF a...
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