RESEARCH ARTICLE
Weigh the pros and cons to ovarian reserve before stripping ovarian endometriomas prior to IVF/ICSI: A meta-analysis Xin Tao1☯*, Lei Chen1☯, Shuqi Ge2☯, Lisi Cai1 1 Center for Reproductive Medicine, the Third Affiliated Hospital of Sun-Yet Sen University, Guangzhou, Guangdong Province, China, 2 Department of Infertility and Sexual Medicine, the Third Affiliated Hospital of Sun-Yet Sen University, Guangzhou, Guangdong Province, China ☯ These authors contributed equally to this work. * [email protected]
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Abstract Purpose To explore the effects of conservative surgery for endometriomas on ovarian responsiveness during assisted reproductive technology (ART) and provide reproductive and gynecological doctors with a more reliable reference program for the treatment of endometriomas.
OPEN ACCESS Citation: Tao X, Chen L, Ge S, Cai L (2017) Weigh the pros and cons to ovarian reserve before stripping ovarian endometriomas prior to IVF/ICSI: A meta-analysis. PLoS ONE 12(6): e0177426. https://doi.org/10.1371/journal.pone.0177426 Editor: Wan-Xi Yang, Zhejiang University College of Life Sciences, CHINA
Methods A literature search was performed by searching the PubMed, Embase, Cochrane Library, Web of Science and Science Direct databases. Studies with inter- and intra-patient comparisons of ovarian responses and oocyte quality between operated and unoperated ovaries and that met the inclusion criteria were retrieved, and the data from the outcome measures were extracted and pooled for this meta-analysis.
Received: January 15, 2017
Results
Accepted: April 27, 2017
Twenty-one published studies (2649 ART cycles) were included. The total amount of gonadotropin (Gn) used (inverse variance (IV):0.48; 95% confidence interval (CI): [0.13, 1.82], P = 0.0007) was significantly increased in the women with endometriomas who had a history of cystectomy. The estrogen (E) level on the day of hCG administration (IV: -0.29; 95% CI: [-0.41, -0.17], P
Weigh the pros and cons to ovarian reserve before stripping ovarian endometriomas prior to IVF/ICSI: A meta-analysis Xin Tao1☯*, Lei Chen1☯, Shuqi Ge2☯, Lisi Cai1 1 Center for Reproductive Medicine, the Third Affiliated Hospital of Sun-Yet Sen University, Guangzhou, Guangdong Province, China, 2 Department of Infertility and Sexual Medicine, the Third Affiliated Hospital of Sun-Yet Sen University, Guangzhou, Guangdong Province, China ☯ These authors contributed equally to this work. * [email protected]
a1111111111 a1111111111 a1111111111 a1111111111 a1111111111
Abstract Purpose To explore the effects of conservative surgery for endometriomas on ovarian responsiveness during assisted reproductive technology (ART) and provide reproductive and gynecological doctors with a more reliable reference program for the treatment of endometriomas.
OPEN ACCESS Citation: Tao X, Chen L, Ge S, Cai L (2017) Weigh the pros and cons to ovarian reserve before stripping ovarian endometriomas prior to IVF/ICSI: A meta-analysis. PLoS ONE 12(6): e0177426. https://doi.org/10.1371/journal.pone.0177426 Editor: Wan-Xi Yang, Zhejiang University College of Life Sciences, CHINA
Methods A literature search was performed by searching the PubMed, Embase, Cochrane Library, Web of Science and Science Direct databases. Studies with inter- and intra-patient comparisons of ovarian responses and oocyte quality between operated and unoperated ovaries and that met the inclusion criteria were retrieved, and the data from the outcome measures were extracted and pooled for this meta-analysis.
Received: January 15, 2017
Results
Accepted: April 27, 2017
Twenty-one published studies (2649 ART cycles) were included. The total amount of gonadotropin (Gn) used (inverse variance (IV):0.48; 95% confidence interval (CI): [0.13, 1.82], P = 0.0007) was significantly increased in the women with endometriomas who had a history of cystectomy. The estrogen (E) level on the day of hCG administration (IV: -0.29; 95% CI: [-0.41, -0.17], P
