J Fluoresc (2014) 24:1495–1501 DOI 10.1007/s10895-014-1435-7
ORIGINAL PAPER
Highly Sensitive Fluorescent Probe for Clenbuterol Hydrochloride Detection Based on its Catalytic Oxidation of Eosine Y by NaIO4 Jiaming Liu & Zhen-bo Liu & Qitong Huang & Chang-Qing Lin & Xiaofeng Lin
Received: 29 April 2014 / Accepted: 11 August 2014 / Published online: 27 August 2014 # Springer Science+Business Media New York 2014
Abstract A highly sensitive fluorescent probe for clenbuterol hydrochloride (CLB) detection has been first designed based on its catalytic effect on NaIO4 oxidating eosine Y (R). And this environment-friendly, simple, rapid, selective and sensitive fluorescent probe has been utilized to detect CLB in the practical samples with the results consisting with those obtained by GC/MS. The structures of R and CLB were characterized by infrared spectra. The mechanism of the proposed assay for the detection of CLB was also discussed. Keywords Clenbuterol hydrochloride . Eosine Y . Fluorescent probe
Introduction Clenbuterol hydrochloride (CLB) is one of the β2-adrenergic agonists, it originally used as a drug for the treatment of pulmonary disease and asthma [1, 2]. However, it is illegally applied as nutrient repartitioning agents in livestock to greatly reduce fat levels and increase muscle protein [3, 4]. On account of the potential risk to consumers for adverse cardiovascular and central nervous system effects [5–7], CLB is not J. Liu (*) : X. Lin College of Chemistry and Environmental, Minnan Normal University, Zhangzhou 363000, People’s Republic of China e-mail: [email protected] Z.
ORIGINAL PAPER
Highly Sensitive Fluorescent Probe for Clenbuterol Hydrochloride Detection Based on its Catalytic Oxidation of Eosine Y by NaIO4 Jiaming Liu & Zhen-bo Liu & Qitong Huang & Chang-Qing Lin & Xiaofeng Lin
Received: 29 April 2014 / Accepted: 11 August 2014 / Published online: 27 August 2014 # Springer Science+Business Media New York 2014
Abstract A highly sensitive fluorescent probe for clenbuterol hydrochloride (CLB) detection has been first designed based on its catalytic effect on NaIO4 oxidating eosine Y (R). And this environment-friendly, simple, rapid, selective and sensitive fluorescent probe has been utilized to detect CLB in the practical samples with the results consisting with those obtained by GC/MS. The structures of R and CLB were characterized by infrared spectra. The mechanism of the proposed assay for the detection of CLB was also discussed. Keywords Clenbuterol hydrochloride . Eosine Y . Fluorescent probe
Introduction Clenbuterol hydrochloride (CLB) is one of the β2-adrenergic agonists, it originally used as a drug for the treatment of pulmonary disease and asthma [1, 2]. However, it is illegally applied as nutrient repartitioning agents in livestock to greatly reduce fat levels and increase muscle protein [3, 4]. On account of the potential risk to consumers for adverse cardiovascular and central nervous system effects [5–7], CLB is not J. Liu (*) : X. Lin College of Chemistry and Environmental, Minnan Normal University, Zhangzhou 363000, People’s Republic of China e-mail: [email protected] Z.
