Clin. exp. Immunol. (1991) 84, 48-52

ADONIS 000991049100102L

Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease S. RATANACHAIYAVONG, A. G. DEMAINE, R. D. CAMPBELL* & A. M. McGREGOR Department of Medicine, King's College School of Medicine and Dentistry, London, UK, and *MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, Oxford, UK

(Acceptedfor publication 2 November 1990)

SUMMARY The genetic polymorphisms of the heat shock protein 70 (HSP70) and complement component C4 were investigated in 90 patients with hyperthyroid Graves' disease and 92 normal control subjects. The 8-5-kb PstI HSP70 allele was strongly associated with Graves' disease when compared with controls (P

Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease.

The genetic polymorphisms of the heat shock protein 70 (HSP70) and complement component C4 were investigated in 90 patients with hyperthyroid Graves' ...
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