Research Article
Health-related quality of life, depression, and anxiety in patients with autoimmune hepatitis Christoph Schramm1,⇑, , Inka Wahl2,3, , Christina Weiler-Normann1, Katharina Voigt2,3, Christiane Wiegard1, Claudia Glaubke1, Elmar Brähler4, Bernd Löwe2,3, Ansgar W. Lohse1, Matthias Rose2,3 1 Ist Department of Medicine, University Medical Center Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; 2Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; 3 Schön Klinik Hamburg Eilbek, Dehnhaide 120, 22081 Hamburg, Germany; 4Department of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Str 55, 04103 Leipzig, Germany
Background & Aims: Improving health related quality of life (HrQoL) in patients with chronic diseases such as autoimmune hepatitis (AIH) should be a major treatment goal. However, little is known on the HrQoL in patients with AIH, and the topic is not given attention in current practice guidelines. We therefore conducted a single center study evaluating HrQoL in 103 consecutive outpatients with AIH. Methods: Patient-reported HrQoL data were analysed in relation to clinical disease parameters and compared to representative data of the German population as well as control patients. Results: Based on patient-reported data, a major depressive syndrome (10.8%) was found to be five times more frequent in AIH patients compared to the general population (p
Health-related quality of life, depression, and anxiety in patients with autoimmune hepatitis Christoph Schramm1,⇑, , Inka Wahl2,3, , Christina Weiler-Normann1, Katharina Voigt2,3, Christiane Wiegard1, Claudia Glaubke1, Elmar Brähler4, Bernd Löwe2,3, Ansgar W. Lohse1, Matthias Rose2,3 1 Ist Department of Medicine, University Medical Center Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; 2Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; 3 Schön Klinik Hamburg Eilbek, Dehnhaide 120, 22081 Hamburg, Germany; 4Department of Medical Psychology and Medical Sociology, University of Leipzig, Philipp-Rosenthal-Str 55, 04103 Leipzig, Germany
Background & Aims: Improving health related quality of life (HrQoL) in patients with chronic diseases such as autoimmune hepatitis (AIH) should be a major treatment goal. However, little is known on the HrQoL in patients with AIH, and the topic is not given attention in current practice guidelines. We therefore conducted a single center study evaluating HrQoL in 103 consecutive outpatients with AIH. Methods: Patient-reported HrQoL data were analysed in relation to clinical disease parameters and compared to representative data of the German population as well as control patients. Results: Based on patient-reported data, a major depressive syndrome (10.8%) was found to be five times more frequent in AIH patients compared to the general population (p
