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HÆMOPHILUS INFLUENZÆ AND
HÆMOPHILUS PARAINFLUENZÆ IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE CHARLES B. SMITH RICHARD E. KANNER
CAROLE A. GOLDEN ATTILIO D. RENZETTI
Department of Internal Medicine, University of Utah College of Medicine, Salt Lake City, Utah 84132, U.S.A. The importance of nonencapsulated strains of Hœmophilus influenzœ and H. parainfluenzœ in the pathogenesis of chronic obstructive pulmonary disease (C.O.P.D.) has been investigated in 150 patients observed at two-month intervals from 1968 to 1975. H. influenzœ was distinguished from H. parainfluenzœ by demonstrating requirements for both X and V factors. H. influenzœ was isolated more often from sputum cultures from patients with severe C.O.P.D. (13·8%) than from patients with mild disease (4·4%, P
HÆMOPHILUS INFLUENZÆ AND
HÆMOPHILUS PARAINFLUENZÆ IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE CHARLES B. SMITH RICHARD E. KANNER
CAROLE A. GOLDEN ATTILIO D. RENZETTI
Department of Internal Medicine, University of Utah College of Medicine, Salt Lake City, Utah 84132, U.S.A. The importance of nonencapsulated strains of Hœmophilus influenzœ and H. parainfluenzœ in the pathogenesis of chronic obstructive pulmonary disease (C.O.P.D.) has been investigated in 150 patients observed at two-month intervals from 1968 to 1975. H. influenzœ was distinguished from H. parainfluenzœ by demonstrating requirements for both X and V factors. H. influenzœ was isolated more often from sputum cultures from patients with severe C.O.P.D. (13·8%) than from patients with mild disease (4·4%, P
