Journal of Clinical Imaging Science
Editor‑in‑Chief: Vikram S. Dogra, MD OPEN ACCESS Department of Imaging Sciences, University of HTML format Rochester Medical Center, Rochester, USA For entire Editorial Board visit : www.clinicalimagingscience.org/editorialboard.asp www.clinicalimagingscience.org
RADIOLOGIC‑PATHOLOGIC CORRELATION
Giant Renal Angiomyolipoma: Unusual Cause of Huge Abdominal Mass Rajesh Taneja, Dig Vijay Singh1 Departments of Urology, Indraprastha Apollo Hospitals, New Delhi, 1Mohandai Oswal Hospital, Ludhiana, Punjab, India Address for correspondence: Dr. Dig Vijay Singh, Department of Urology, Mohandai Oswal Hospital, Ludhiana ‑ 141 010, Punjab, India. E‑mail: [email protected]
Received: 12‑08‑2013
ABSTRACT We present the imaging and histopathological characteristics of a giant renal angiomyolipoma (AML) in a 49‑year‑old female patient, who presented with bloating sensation in the abdomen and a steadily increasing abdominal girth for about 3 years. Contrast enhanced computed tomography (CECT) scan films of abdomen revealed that a large fat containing tumor had replaced the left kidney while displacing the rest of the abdominal contents toward the other side of the midline. Intraoperatively the left kidney was completely replaced by a fat containing tumor. The recovered surgical specimen measured 39 cm × 25 cm × 9 cm and weighed 7500 g. Histopathological investigation with immuno‑histochemical staining of the specimen with hydroxy beta‑methylbutyric acid‑45 confirmed this lesion as AML. CECT scan of the head did not show any lesion suggestive of tuberous sclerosis. The giant tumor of the present case is the heaviest AML in both syndromic and sporadic categories and largest by dimensions as sporadic AML ever reported in the literature.
Key words: Angiomyolipoma, giant kidney tumor, heaviest renal angiomyolipoma,
Accepted: 21‑10‑2013
sporadic tuberous sclerosis
Published: 28-11-2013
INTRODUCTION
RADIOLOGIC FEATURES
Renal angiomyolipoma (AML) is an infrequent tumor that, in most cases, follows a benign course and has clearly defined radiological and histological characteristics.[1] We present a case of giant renal AML, which is the heaviest ever reported, encountered in a tertiary care hospital in India.
A 49‑year‑old lady, a native of Afghanistan, presented with a 3‑year history of steadily increasing abdominal girth and bloating sensation in the abdomen. She also experienced intermittent dull ache in the left flank. She underwent investigation in another institute and was found to have a huge abdominal mass. Review of contrast enhanced computed tomography (CECT) scans of abdomen revealed a large fat containing tumor measuring 40 cm × 24 cm × 10 cm (
Editor‑in‑Chief: Vikram S. Dogra, MD OPEN ACCESS Department of Imaging Sciences, University of HTML format Rochester Medical Center, Rochester, USA For entire Editorial Board visit : www.clinicalimagingscience.org/editorialboard.asp www.clinicalimagingscience.org
RADIOLOGIC‑PATHOLOGIC CORRELATION
Giant Renal Angiomyolipoma: Unusual Cause of Huge Abdominal Mass Rajesh Taneja, Dig Vijay Singh1 Departments of Urology, Indraprastha Apollo Hospitals, New Delhi, 1Mohandai Oswal Hospital, Ludhiana, Punjab, India Address for correspondence: Dr. Dig Vijay Singh, Department of Urology, Mohandai Oswal Hospital, Ludhiana ‑ 141 010, Punjab, India. E‑mail: [email protected]
Received: 12‑08‑2013
ABSTRACT We present the imaging and histopathological characteristics of a giant renal angiomyolipoma (AML) in a 49‑year‑old female patient, who presented with bloating sensation in the abdomen and a steadily increasing abdominal girth for about 3 years. Contrast enhanced computed tomography (CECT) scan films of abdomen revealed that a large fat containing tumor had replaced the left kidney while displacing the rest of the abdominal contents toward the other side of the midline. Intraoperatively the left kidney was completely replaced by a fat containing tumor. The recovered surgical specimen measured 39 cm × 25 cm × 9 cm and weighed 7500 g. Histopathological investigation with immuno‑histochemical staining of the specimen with hydroxy beta‑methylbutyric acid‑45 confirmed this lesion as AML. CECT scan of the head did not show any lesion suggestive of tuberous sclerosis. The giant tumor of the present case is the heaviest AML in both syndromic and sporadic categories and largest by dimensions as sporadic AML ever reported in the literature.
Key words: Angiomyolipoma, giant kidney tumor, heaviest renal angiomyolipoma,
Accepted: 21‑10‑2013
sporadic tuberous sclerosis
Published: 28-11-2013
INTRODUCTION
RADIOLOGIC FEATURES
Renal angiomyolipoma (AML) is an infrequent tumor that, in most cases, follows a benign course and has clearly defined radiological and histological characteristics.[1] We present a case of giant renal AML, which is the heaviest ever reported, encountered in a tertiary care hospital in India.
A 49‑year‑old lady, a native of Afghanistan, presented with a 3‑year history of steadily increasing abdominal girth and bloating sensation in the abdomen. She also experienced intermittent dull ache in the left flank. She underwent investigation in another institute and was found to have a huge abdominal mass. Review of contrast enhanced computed tomography (CECT) scans of abdomen revealed a large fat containing tumor measuring 40 cm × 24 cm × 10 cm (
