Brain Research, 530 (1990) 235-238
235
Elsevier BRES 15935
Gastrin, cholecystokinin and their precursors in acoustic neuromas J.F. Rehfeld 1'2, W.W. van Solinge 1, M.
T o s 2'3
and J. T h o m s e n 2'3
Departments of 1Clinical Chemistry and 2Neurosurgery, Righospitalet, Copenhagen (Denmark) and 3Department of Otolaryngology, Copenhagen County Hospital in Gentofte, University of Copenhagen, Copenhagen (Denmark) (Accepted 24 April 1990)
Key words: Biosynthesis; Brain nerve, Cholecystokinin; Gastrin; Nerve tumor; Neuropeptide
Using sequence-specific radioimmunoassays the occurrence of 4 neuropeptides (cholecystokinin (CCK), gastrin, somatostatin, substance P and some of their precursors) was examined in 19 human acoustic nerve tumors and corresponding normal tissue. The normal acoustic nerve tissue obtained by autopsy contained traces of CCK, somatostatin, and substance P (~
235
Elsevier BRES 15935
Gastrin, cholecystokinin and their precursors in acoustic neuromas J.F. Rehfeld 1'2, W.W. van Solinge 1, M.
T o s 2'3
and J. T h o m s e n 2'3
Departments of 1Clinical Chemistry and 2Neurosurgery, Righospitalet, Copenhagen (Denmark) and 3Department of Otolaryngology, Copenhagen County Hospital in Gentofte, University of Copenhagen, Copenhagen (Denmark) (Accepted 24 April 1990)
Key words: Biosynthesis; Brain nerve, Cholecystokinin; Gastrin; Nerve tumor; Neuropeptide
Using sequence-specific radioimmunoassays the occurrence of 4 neuropeptides (cholecystokinin (CCK), gastrin, somatostatin, substance P and some of their precursors) was examined in 19 human acoustic nerve tumors and corresponding normal tissue. The normal acoustic nerve tissue obtained by autopsy contained traces of CCK, somatostatin, and substance P (~
