Editorial
From the Editor's desk Madhuri Patil Editor‑in‑Chief, Journal of Human Reproductive Sciences E‑mail: drmadhuripatil59@ gmail.com Received: 13.12.2014 Review completed: 13.12.2014 Accepted: 13.12.2014
The review article is on newer gonadotropins available for controlled ovarian stimulation and how it has changed the management of assisted reproductive technique (ART) cycles. It also discusses on research molecules that are being developed for parenteral, transdermal, inhalation and oral use, which will further simplify treatment for ART. The other review article is on how to optimize “batch in vitro fertilization (IVF)” in an antagonist cycle. In India due to scarcity of embryologist, IVF center’s in small places schedule their patients in such a way that a group of patients undergo oocyte retrieval and embryo transfer over a period of three to four days. This was easy when most units were using the GnRH agonist long protocol. But today most centers are using the GnRH antagonist protocol as it reduces the incidence of ovarian hyper stimulation syndrome (OHSS) and is also more patient friendly. This article reviews the use of oral contraceptive pills, estrogens and progesterone’s to synchronize the menstrual cycles of patients undergoing “batch IVF. A retrospective survey of reasons for discontinuation of IVF treatment among couples attending an infertility clinic in one of the sub-urban of a metropolitan city is analyzed. In India there is a mixed socioeconomic strata. In the poor class and lower middle class the financial burden of In vitro fertilization (IVF) makes acceptance of treatment difficult. Even if they undergo one cycle it is very difficult for them to come for repeated cycle. This article will probably prompt the IVF specialist in India and the government to start low cost ART centers in association with the NGOs. Today the incidence of polycystic ovaries (PCOS) has increased considerably and this is related in large to our lifestyle. Though lifestyle modification is the first and best option in PCOS to help patient succeed in ovulation and achieving a pregnancy, but it is the most difficult one. We have an original paper, which compares the effects of Orlistat with metformin and exercise on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in PCOS. This study finds Orlistat as effective as metformin in reducing weight and achieves similar ovulation rates in obese PCOS patients.
Access this article online Quick Response Code:
Website: www.jhrsonline.org DOI: 10.4103/0974-1208.147488
Recurrent pregnancy loss, especially in the sub-fertile population is a great problem. Here we need to find the cause and treat the patient accordingly. Many times no cause is found when both the partners are investigated. At times these losses could be related to aneuploidies in the fetus and this could be easily identified if the chorionic tissue at suction evacuation, is sent for cytogenetic analysis. The retrospective study published in this issue found that the cytogenetic abnormalities revealed high percentage of double (4.6%) and multiple (0.4%) aneuploidies, frequently involving the acrocentric chromosomes 13, 15, 21, and 22 and no acrocentric chromosomes X, 16, and 18. We have three case reports, one on primary umbilical endometriosis and the other two are on abnormalities of mullerian duct. One deals with the use of custom fabricated acrylic vaginal stent as an adjuvant to surgical creation of neovagina for a young female with isolated vaginal agenesis and the other on spontaneous conception in a patient of transverse vaginal septum, which was diagnosed during labor along with unicornuate uterus diagnosed at cesarean section.
How to cite this article: Patil M. From the Editor's desk. J Hum Reprod Sci 2014;7:229.
Journal of Human Reproductive Sciences / Volume 7 / Issue 4 / Oct - Dec 2014
229
Copyright of Journal of Human Reproductive Sciences is the property of Medknow Publications & Media Pvt. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
From the Editor's desk Madhuri Patil Editor‑in‑Chief, Journal of Human Reproductive Sciences E‑mail: drmadhuripatil59@ gmail.com Received: 13.12.2014 Review completed: 13.12.2014 Accepted: 13.12.2014
The review article is on newer gonadotropins available for controlled ovarian stimulation and how it has changed the management of assisted reproductive technique (ART) cycles. It also discusses on research molecules that are being developed for parenteral, transdermal, inhalation and oral use, which will further simplify treatment for ART. The other review article is on how to optimize “batch in vitro fertilization (IVF)” in an antagonist cycle. In India due to scarcity of embryologist, IVF center’s in small places schedule their patients in such a way that a group of patients undergo oocyte retrieval and embryo transfer over a period of three to four days. This was easy when most units were using the GnRH agonist long protocol. But today most centers are using the GnRH antagonist protocol as it reduces the incidence of ovarian hyper stimulation syndrome (OHSS) and is also more patient friendly. This article reviews the use of oral contraceptive pills, estrogens and progesterone’s to synchronize the menstrual cycles of patients undergoing “batch IVF. A retrospective survey of reasons for discontinuation of IVF treatment among couples attending an infertility clinic in one of the sub-urban of a metropolitan city is analyzed. In India there is a mixed socioeconomic strata. In the poor class and lower middle class the financial burden of In vitro fertilization (IVF) makes acceptance of treatment difficult. Even if they undergo one cycle it is very difficult for them to come for repeated cycle. This article will probably prompt the IVF specialist in India and the government to start low cost ART centers in association with the NGOs. Today the incidence of polycystic ovaries (PCOS) has increased considerably and this is related in large to our lifestyle. Though lifestyle modification is the first and best option in PCOS to help patient succeed in ovulation and achieving a pregnancy, but it is the most difficult one. We have an original paper, which compares the effects of Orlistat with metformin and exercise on anthropometric parameters, lipid profile, endocrine parameters, and ovulation in PCOS. This study finds Orlistat as effective as metformin in reducing weight and achieves similar ovulation rates in obese PCOS patients.
Access this article online Quick Response Code:
Website: www.jhrsonline.org DOI: 10.4103/0974-1208.147488
Recurrent pregnancy loss, especially in the sub-fertile population is a great problem. Here we need to find the cause and treat the patient accordingly. Many times no cause is found when both the partners are investigated. At times these losses could be related to aneuploidies in the fetus and this could be easily identified if the chorionic tissue at suction evacuation, is sent for cytogenetic analysis. The retrospective study published in this issue found that the cytogenetic abnormalities revealed high percentage of double (4.6%) and multiple (0.4%) aneuploidies, frequently involving the acrocentric chromosomes 13, 15, 21, and 22 and no acrocentric chromosomes X, 16, and 18. We have three case reports, one on primary umbilical endometriosis and the other two are on abnormalities of mullerian duct. One deals with the use of custom fabricated acrylic vaginal stent as an adjuvant to surgical creation of neovagina for a young female with isolated vaginal agenesis and the other on spontaneous conception in a patient of transverse vaginal septum, which was diagnosed during labor along with unicornuate uterus diagnosed at cesarean section.
How to cite this article: Patil M. From the Editor's desk. J Hum Reprod Sci 2014;7:229.
Journal of Human Reproductive Sciences / Volume 7 / Issue 4 / Oct - Dec 2014
229
Copyright of Journal of Human Reproductive Sciences is the property of Medknow Publications & Media Pvt. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
