Abstracts S159
The veteran athlete Saturday, 16 May 2015, 08:30–10:00 711 Long-term intense endurance exercise is not associated with subclinical vascular organ damage - a comprehensive analysis
A Axel Pressler1, C Suchy1, T Friedrichs1, S Dallinger1, M Dinic1, M Halle1, J Scherr1 Technical University of Munich, Department of Prevention and Sports Medicine, Munich, Germany
1
Topic: Sports cardiology Purpose: Contrasting the well-accepted beneficial effects of moderate exercise, recent research has suggested potential deleterious effects of long-term endurance exercise on the cardiovascular system. We thus performed a comprehensive analysis of markers of subclinical vascular organ damage in a cohort of runners having finished multiple marathon races successfully. Methods: A total of 162 non-smoking, normotensive healthy male runners (mean age 4211 years) underwent detailed training history, cardiopulmonary exercise testing for assessment of peak oxygen uptake (VO2peak) and ultrasound assessment of intima-media-thickness (IMT) shortly prior to participation in the Munich marathon 2013. A subgroup of 99 runners also
underwent assessment of ankle-brachial index (ABI), augmentation index (AIx; SphygmoCor), pulse wave velocity (PWV; Vascular Explorer) and reactive hyperemia index (RHI; EndoPAT) within a short time frame after the race. Results: Runners had previously completed a median of 3 (IQR 10; range 0-500) half- and 3 (8; 0-100) full marathons; 18 runners had also completed 4 (6; 1-40) ultramarathons; weekly and annual training volumes were 5623 and 1548941 km, respectively. VO2peak was 518 ml/ min/kg, and the race itself was finished in 3:450:36 hours. Runners showed normal values for IMT (0.590.13mm), ABI (1.20.1), AIx (1713%), PWV (8.71.4cm/s) and RHI (1.950.05). Age was the strongest predictor for all of these markers, whereas no associations were observed for VO2peak, finishing time, number of completed half-, full or ultramarathons or weekly and annual training kilometers. Conclusion: Long-term endurance exercise does not result in premature subclinical vascular organ damage.
Downloaded from cpr.sagepub.com by guest on November 17, 2015
The veteran athlete Saturday, 16 May 2015, 08:30–10:00 711 Long-term intense endurance exercise is not associated with subclinical vascular organ damage - a comprehensive analysis
A Axel Pressler1, C Suchy1, T Friedrichs1, S Dallinger1, M Dinic1, M Halle1, J Scherr1 Technical University of Munich, Department of Prevention and Sports Medicine, Munich, Germany
1
Topic: Sports cardiology Purpose: Contrasting the well-accepted beneficial effects of moderate exercise, recent research has suggested potential deleterious effects of long-term endurance exercise on the cardiovascular system. We thus performed a comprehensive analysis of markers of subclinical vascular organ damage in a cohort of runners having finished multiple marathon races successfully. Methods: A total of 162 non-smoking, normotensive healthy male runners (mean age 4211 years) underwent detailed training history, cardiopulmonary exercise testing for assessment of peak oxygen uptake (VO2peak) and ultrasound assessment of intima-media-thickness (IMT) shortly prior to participation in the Munich marathon 2013. A subgroup of 99 runners also
underwent assessment of ankle-brachial index (ABI), augmentation index (AIx; SphygmoCor), pulse wave velocity (PWV; Vascular Explorer) and reactive hyperemia index (RHI; EndoPAT) within a short time frame after the race. Results: Runners had previously completed a median of 3 (IQR 10; range 0-500) half- and 3 (8; 0-100) full marathons; 18 runners had also completed 4 (6; 1-40) ultramarathons; weekly and annual training volumes were 5623 and 1548941 km, respectively. VO2peak was 518 ml/ min/kg, and the race itself was finished in 3:450:36 hours. Runners showed normal values for IMT (0.590.13mm), ABI (1.20.1), AIx (1713%), PWV (8.71.4cm/s) and RHI (1.950.05). Age was the strongest predictor for all of these markers, whereas no associations were observed for VO2peak, finishing time, number of completed half-, full or ultramarathons or weekly and annual training kilometers. Conclusion: Long-term endurance exercise does not result in premature subclinical vascular organ damage.
Downloaded from cpr.sagepub.com by guest on November 17, 2015
