THE USE OF THE LIGATURE AND CARBOLIC ACID IN THE TREATMENT OF

EXPERIMENTS ON SNAKE-BITES. By J.

Faykek, M.D., C.S.I. Sceva.?July 17th,

PresentDe. Eayeee and Me.

1869.

Expeeiment No. 1. A

large

and

2-45 p.m.,

by

powerful pariah dog was bitten in the thigh, at a fresh cobra (keautiah). The hair had been

removed from the part in order that the puncture of the snake's fangs might be distinctly seen. The moment the fangs were withdrawn, the punctures were scarified, and

previously

applied, and well inoculated into the bites. -whitened, and the blood coagulated by the acid. 2-53 p.m.?The dog looks depressed and dejected; hanging his head. 3-12.?Lying down; looks dejected, but perfectly intelligent. 3-15.?Respiration hurried. 3-23?Pupils widely dilated. In convulsions, rolled over on the other side; respiration irregular and catching. 3-27.?Violently convulsed. 3-30.?Respiration lias ceased, but the heart still beats distinctly. 3-31.?Dead in forty-sis minutes. The carbolic acid was evidently of no service in this case. Post-mortem, examination at 5 p.m. Blood coagulated; no crystallization under microscope.

carbolic acid at once The tissues

were

Expeeiment No. 2. A fowl had the feathers removed from the thigh, so that tho bites might be seen, and was then bitten there at 2-54 p.m. by a daboia. The wounds were immediately scarified, and the carbolic acid thoroughly applied to the bites. The fowl fell over in convulsions when released, and was dead in less than sixty seconds. The in about 40 minutes after

body was opened at 3-35, or death, and the blood was found to be coagulated in the heart and great vessels ; some fluid blood escaped into tho thorax. The lungs were not in the least congested. The condition of the blood was particularly noted, as it has generally been found fluid in the mammals dead from the daboia-bite.

Post-mortem, examination of dog, experiment No. 3. Blood examined at 5 p.m.: fluid when removed, but coagu* lated on exposure to the air. Microscopical examination: no crystals ; no change. Expeeiment No. 3. The

poison

of

a

fresh cobra

(gokurrah)

was

taken from

the snake in my presence, and ten drops of it immediatcy

SErTEMBEK 1,

18G9.] LIGATURE, &c.,

IN TREATMENT OF SNAIvE-BITES.?BY J. FATHER.

injected with the hypodermic syringe into a middling-sized dog's thigh, at 3-3 p.m. The tube of the hypodermic syringe was not removed ; and the syringe being filled with carbolic acid, about 20 drops were injected exactly in the track of the poison, and in the shortest space of time possible. 3-8?The dog is depressed ; looks scared; hangs his head; twitching of the hind legs when he is raised. 3-15?Lying on his side almost paralysed ; pupils widely dilated. 3-20?Is convulsed. 3-22?General twitching of all the muscles of the body ; is quite unconscious. Respiration has ceased, but tho heart still beats distinctly. 3-25?Heart still beats. 3-27.-?

Irregular action of heart. 3-29?Dead in 2G minutes. In this case there could bo no doubt of the perfect inoculation of tho carbolic acid, for it followed the poison through the same

and in the shortest possible spaco of time, in which any local remedy could be applied, and yet without producing the slightest benefit. The second of time by which the

Experiment No. 9. A varauus flavesccna was bitten by another daboin, nt 4-15 p.m. The dnboia had bitten before. He did not strike hia fangs readily through the hard skin of tho lizard. 18th July, 3 p.m.?No G

Experiment No. 4, A fowl

bitten in the

was

The carbolic acid

was

thigh by a daboia at 3-19 p.m. immediately applied to the" wounds which

had been at once scarified. 3-20.?Dead in and

great

3-19-30?Fowl in convulsions.

minute.

Body opened. coagulated.

one

vessels had

Blood

in heart

Experiment No. 5. A small dog bitten in the thigh, by a bungarus fasciatus, (one used last week) at 3-13 p.m. The bites drew blood. 3-29?Looks dejected. 5-20?No further change. 18

Experiments on the Use of the Ligature and Carbolic Acid in the Treatment of Snake-Bites.

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