Journal of Cancer 2017, Vol. 8
Ivyspring
International Publisher
Research Paper
1665
Journal of Cancer
2017; 8(9): 1665-1672. doi: 10.7150/jca.19197
Evaluation of 7th Edition of AJCC Staging System for Nasopharyngeal Carcinoma YuFeng Ren1*, Huizhi Qiu2*, Yujie Yuan3, Jinning Ye3, Yunhong Tian2, Bixiu Wen1, Weijun Zhang2 and Qun Li4, 5 1. 2. 3. 4. 5.
Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China; Department of Radiotherapy, cancer center of Guangzhou medical university, Guangzhou 510080, P.R.China; Center of Gastrointestinal Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, P.R.China; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, P. R. China.
* These authors contributed equally to this work. Corresponding author: Qun Li., M.D., Ph.D; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, P. R. China; Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, P.R.China. E-mail: [email protected] © Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Received: 2017.01.15; Accepted: 2017.03.31; Published: 2017.06.03
Abstract Purpose: To evaluate and improve the 7th edition International Union against Cancer/American Joint Committee on Cancer staging system for nasopharyngeal carcinoma. Methods: A retrospective review of the data from 905 patients with biopsy-proven non-disseminated nasopharyngeal carcinoma was performed. All the patients were examined by magnetic resonance imaging (MRI) and received radiotherapy. Results: Satisfied distributions among the stages were observed in the 7th edition staging systems. LRFS only differed in classifications betweenT1 and T3, T1 and T4 (P=0.022 and P=0.016, respectively). Significant differences were observed between patients without and with masticator space involvement for OS, DMFS and PFS (p
Ivyspring
International Publisher
Research Paper
1665
Journal of Cancer
2017; 8(9): 1665-1672. doi: 10.7150/jca.19197
Evaluation of 7th Edition of AJCC Staging System for Nasopharyngeal Carcinoma YuFeng Ren1*, Huizhi Qiu2*, Yujie Yuan3, Jinning Ye3, Yunhong Tian2, Bixiu Wen1, Weijun Zhang2 and Qun Li4, 5 1. 2. 3. 4. 5.
Department of Radiation Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China; Department of Radiotherapy, cancer center of Guangzhou medical university, Guangzhou 510080, P.R.China; Center of Gastrointestinal Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, P.R.China; Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, P.R.China; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, P. R. China.
* These authors contributed equally to this work. Corresponding author: Qun Li., M.D., Ph.D; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong, P. R. China; Department of Radiation Oncology, Cancer Center, Sun Yat-sen University, Guangzhou 510060, P.R.China. E-mail: [email protected] © Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
Received: 2017.01.15; Accepted: 2017.03.31; Published: 2017.06.03
Abstract Purpose: To evaluate and improve the 7th edition International Union against Cancer/American Joint Committee on Cancer staging system for nasopharyngeal carcinoma. Methods: A retrospective review of the data from 905 patients with biopsy-proven non-disseminated nasopharyngeal carcinoma was performed. All the patients were examined by magnetic resonance imaging (MRI) and received radiotherapy. Results: Satisfied distributions among the stages were observed in the 7th edition staging systems. LRFS only differed in classifications betweenT1 and T3, T1 and T4 (P=0.022 and P=0.016, respectively). Significant differences were observed between patients without and with masticator space involvement for OS, DMFS and PFS (p
