diabetes research and clinical practice 108 (2015) e14–e17

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Diabetes Research and Clinical Practice jou rnal hom ep ag e: w ww.e l s e v i er . c om/ loca te / d i ab r es

International Diabetes Federation

Variation in the relationship between gestational diabetes diagnosis and total gestational weight gain by race/ethnicity Rosette J. Chakkalakal a,b,*, Tebeb Gebretsadik b,c, Shubhada Jagasia a, Ayumi Shintani b,c, Tom A. Elasy a,b a

Department of Medicine, Vanderbilt University, Nashville, TN, United States Vanderbilt Center for Diabetes Translational Research, Vanderbilt University, Nashville, TN, United States c Department of Biostatistics, Vanderbilt University, Nashville, TN, United States b

article info

abstract

Article history:

Prior research suggests that women diagnosed and treated for gestational diabetes mellitus

Received 2 September 2014

(GDM) gain less total gestational weight than normoglycemic women. Our study finds that

Received in revised form

race/ethnicity modifies this association. Relative to normoglycemic women, non-Hispanic

1 November 2014

white women with GDM gain less weight but non-Hispanic black and Hispanic women gain

Accepted 2 January 2015

more weight. # 2015 Elsevier Ireland Ltd. All rights reserved.

Available online 21 January 2015 Keywords: Gestational diabetes Weight gain Minority health

1.

Introduction

Compared to women without gestational diabetes mellitus (GDM), women with GDM have higher pre-pregnancy body mass indices [1] and gain more weight during their first trimester [2,3]. Yet institutional chart reviews of women treated for GDM have found that these women experience less weight gain following GDM diagnosis [3,4] and less total gestational weight gain (GWG) [3–5] than their normoglycemic counterparts. Thus, diagnosis and treatment of GDM may have a beneficial ‘‘side effect’’ of controlling GWG [3,6]. Larger studies are needed to better understand the association

between GDM diagnosis and GWG, particularly among African-American and Hispanic women who are at higher risk than non-Hispanic white women for developing GDM and type 2 diabetes after GDM [7,8]. The purpose of this project was to (1) describe the association between GDM diagnosis and total GWG in a statewide database and (2) determine if the association is modified by race/ethnicity.

2.

Materials and methods

We conducted a retrospective cohort study of non-Hispanic white (NHW), non-Hispanic black (NHB) and Hispanic adult

* Corresponding author at: Vanderbilt University, Department of Medicine, 1215 21st Ave South, Suite 6000 MCE, North Tower, Nashville, TN 37232-8300, United States. Tel.: +1 615 936 1010; fax: +1 615 936 1269. E-mail address: [email protected] (R.J. Chakkalakal). http://dx.doi.org/10.1016/j.diabres.2015.01.020 0168-8227/# 2015 Elsevier Ireland Ltd. All rights reserved.

diabetes research and clinical practice 108 (2015) e14–e17

e15

black squares=GDM grey circles=No GDM Model 2: P, Interaction

ethnicity.

Prior research suggests that women diagnosed and treated for gestational diabetes mellitus (GDM) gain less total gestational weight than normoglycemic...
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