diabetes research and clinical practice 108 (2015) e14–e17
Contents available at ScienceDirect
Diabetes Research and Clinical Practice jou rnal hom ep ag e: w ww.e l s e v i er . c om/ loca te / d i ab r es
International Diabetes Federation
Variation in the relationship between gestational diabetes diagnosis and total gestational weight gain by race/ethnicity Rosette J. Chakkalakal a,b,*, Tebeb Gebretsadik b,c, Shubhada Jagasia a, Ayumi Shintani b,c, Tom A. Elasy a,b a
Department of Medicine, Vanderbilt University, Nashville, TN, United States Vanderbilt Center for Diabetes Translational Research, Vanderbilt University, Nashville, TN, United States c Department of Biostatistics, Vanderbilt University, Nashville, TN, United States b
article info
abstract
Article history:
Prior research suggests that women diagnosed and treated for gestational diabetes mellitus
Received 2 September 2014
(GDM) gain less total gestational weight than normoglycemic women. Our study finds that
Received in revised form
race/ethnicity modifies this association. Relative to normoglycemic women, non-Hispanic
1 November 2014
white women with GDM gain less weight but non-Hispanic black and Hispanic women gain
Accepted 2 January 2015
more weight. # 2015 Elsevier Ireland Ltd. All rights reserved.
Available online 21 January 2015 Keywords: Gestational diabetes Weight gain Minority health
1.
Introduction
Compared to women without gestational diabetes mellitus (GDM), women with GDM have higher pre-pregnancy body mass indices [1] and gain more weight during their first trimester [2,3]. Yet institutional chart reviews of women treated for GDM have found that these women experience less weight gain following GDM diagnosis [3,4] and less total gestational weight gain (GWG) [3–5] than their normoglycemic counterparts. Thus, diagnosis and treatment of GDM may have a beneficial ‘‘side effect’’ of controlling GWG [3,6]. Larger studies are needed to better understand the association
between GDM diagnosis and GWG, particularly among African-American and Hispanic women who are at higher risk than non-Hispanic white women for developing GDM and type 2 diabetes after GDM [7,8]. The purpose of this project was to (1) describe the association between GDM diagnosis and total GWG in a statewide database and (2) determine if the association is modified by race/ethnicity.
2.
Materials and methods
We conducted a retrospective cohort study of non-Hispanic white (NHW), non-Hispanic black (NHB) and Hispanic adult
* Corresponding author at: Vanderbilt University, Department of Medicine, 1215 21st Ave South, Suite 6000 MCE, North Tower, Nashville, TN 37232-8300, United States. Tel.: +1 615 936 1010; fax: +1 615 936 1269. E-mail address:
[email protected] (R.J. Chakkalakal). http://dx.doi.org/10.1016/j.diabres.2015.01.020 0168-8227/# 2015 Elsevier Ireland Ltd. All rights reserved.
diabetes research and clinical practice 108 (2015) e14–e17
e15
black squares=GDM grey circles=No GDM Model 2: P, Interaction