BMJ 2015;350:h3252 doi: 10.1136/bmj.h3252 (Published 16 June 2015)
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NEWS Endometriosis is linked to greater risk of complications in pregnancy and birth, study finds Zosia Kmietowicz The BMJ
Women with endometriosis have a higher risk of miscarriage and ectopic pregnancy, a large cohort study in Scotland has found. Women with the condition who maintain a pregnancy for more than 24 weeks face further risks, including a higher risk of placenta praevia, bleeding before and after birth, and caesarean section.
To evaluate pregnancy outcomes researchers used discharge data from all NHS hospitals in Scotland and linked records of women with and without a confirmed diagnosis of endometriosis to their maternity records. Altogether 5375 women with endometriosis were compared with 8280 women without the condition and were followed up for a maximum of 30 years from 1981 to 2010. Lucky Saraswat, consultant gynaecologist at Aberdeen Royal Infirmary, presented the data at the Science Media Centre in London ahead of the annual meeting of the European Society of Human Reproduction and Embryology in Lisbon from 14 to 17 June. The study has been submitted for publication. After adjusting the data for age and previous pregnancy the researchers found that women with endometriosis were nearly three times more likely than those without the condition to have an ectopic pregnancy (adjusted odds ratio 2.7 (95% confidence
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interval 1.09 to 6.72)) and nearly twice as likely to have a miscarriage (1.76 (1.44 to 2.15)).