Upsala Journal of Medical Sciences
ISSN: 0300-9734 (Print) 2000-1967 (Online) Journal homepage: http://www.tandfonline.com/loi/iups20
Emla for Pain Relief During Arterial Cannulation A. Nilsson, K. Danielson, G. Engberg & S. Henneberg To cite this article: A. Nilsson, K. Danielson, G. Engberg & S. Henneberg (1990) Emla for Pain Relief During Arterial Cannulation, Upsala Journal of Medical Sciences, 95:1, 87-94, DOI: 10.3109/03009739009178579 To link to this article: http://dx.doi.org/10.3109/03009739009178579
Published online: 18 Jan 2010.
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Date: 17 March 2016, At: 03:10
Upsala J Med Sci 95: 87-94
Emla for Pain Relief During Arterial Cannulation A double-blind, placebo-controlled study of a lidocaine-prilocaine cream A. Nilsson, K. Danielson, G. Engberg and S. Henneberg Department of Anaesthesiology and Intensive Care, University Hospital, Uppsala and ASTRA ALAB AB, Sodertalje, Sweden
ABSTRACT
Downloaded by [176.10.99.203] at 03:10 17 March 2016
The aim o f t h e study was t o e v a l u a t e t h e e f f e c t o f a l i d o c a i n e - p r i l o c a i n e cream (EMLA cream, A s t r a l i n r e l i e v i n g p a i n d u r i n g a r t e r i a l c a n n u l a t i o n . The study had a random, double-blind,
p l a c e b o - c o n t r o l l e d design and i n c l u d e d
a l t o g e t h e r 90 p a t i e n t s . A l l t h e p a t i e n t s were premedicated w i t h an o p i o i d b e f o r e c a n n u l a t i o n . An EMLA a p p l i c a t i o n t i m e o f 60 minutes was used i n 60 p a t i e n t s (30 EMLA/30 placebo) and t h e r e was no d i f f e r e n c e i n t h e p a i n r e a c t i o n measured on a v i s u a l analogue s c a l e (VAS) or on an o b s e r v e r ' s v e r b a l scale. The study was extended w i t h a f u r t h e r 30 p a t i e n t s (15 EMLA/15 placebo) with an a p p l i c a t i o n time exceeding 90 minutes. Between these groups p a i n experience measured by VAS d i d n o t show any s i g n i f i c a n t d i f f e r e n c e although t h e mean value was lower i n t h e EMLA group. Observer r a t i n g s showed a
s i g n i f i c a n t (p
ISSN: 0300-9734 (Print) 2000-1967 (Online) Journal homepage: http://www.tandfonline.com/loi/iups20
Emla for Pain Relief During Arterial Cannulation A. Nilsson, K. Danielson, G. Engberg & S. Henneberg To cite this article: A. Nilsson, K. Danielson, G. Engberg & S. Henneberg (1990) Emla for Pain Relief During Arterial Cannulation, Upsala Journal of Medical Sciences, 95:1, 87-94, DOI: 10.3109/03009739009178579 To link to this article: http://dx.doi.org/10.3109/03009739009178579
Published online: 18 Jan 2010.
Submit your article to this journal
Article views: 51
View related articles
Citing articles: 1 View citing articles
Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=iups20 Download by: [176.10.99.203]
Date: 17 March 2016, At: 03:10
Upsala J Med Sci 95: 87-94
Emla for Pain Relief During Arterial Cannulation A double-blind, placebo-controlled study of a lidocaine-prilocaine cream A. Nilsson, K. Danielson, G. Engberg and S. Henneberg Department of Anaesthesiology and Intensive Care, University Hospital, Uppsala and ASTRA ALAB AB, Sodertalje, Sweden
ABSTRACT
Downloaded by [176.10.99.203] at 03:10 17 March 2016
The aim o f t h e study was t o e v a l u a t e t h e e f f e c t o f a l i d o c a i n e - p r i l o c a i n e cream (EMLA cream, A s t r a l i n r e l i e v i n g p a i n d u r i n g a r t e r i a l c a n n u l a t i o n . The study had a random, double-blind,
p l a c e b o - c o n t r o l l e d design and i n c l u d e d
a l t o g e t h e r 90 p a t i e n t s . A l l t h e p a t i e n t s were premedicated w i t h an o p i o i d b e f o r e c a n n u l a t i o n . An EMLA a p p l i c a t i o n t i m e o f 60 minutes was used i n 60 p a t i e n t s (30 EMLA/30 placebo) and t h e r e was no d i f f e r e n c e i n t h e p a i n r e a c t i o n measured on a v i s u a l analogue s c a l e (VAS) or on an o b s e r v e r ' s v e r b a l scale. The study was extended w i t h a f u r t h e r 30 p a t i e n t s (15 EMLA/15 placebo) with an a p p l i c a t i o n time exceeding 90 minutes. Between these groups p a i n experience measured by VAS d i d n o t show any s i g n i f i c a n t d i f f e r e n c e although t h e mean value was lower i n t h e EMLA group. Observer r a t i n g s showed a
s i g n i f i c a n t (p
