Journal of Orthopaedic Research 9683-692 Raven Press, Ltd., New York 0 1991 Orthopaedic Research Society
Electrokinetic Behavior of Intact Wet Bone: Compartmental Model W. R. Walsh and N. Guzelsu Rutgers University Biomedical Engineering Department, SOM Biomechanics Program, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, U.S.A.
Summary: Streaming potential experiments were performed on chemicallytreated intact wet bone plugs equilibrated in potential-determining ion buffers. Comparison of calculated zeta (5) potentials from intact wet bone streaming potentials and bone particle electrophoresis indicates different values. Intact streaming potential experiments, where fluid is forced through the samples, represents flow, primarily through the vascular channel system, and contribution of the organically-lined channels to the electrokinetic potential. Bone particle electrophoresis represents mainly the electrokinetic contribution of exposed mineralized matrix. The organic linings present in the vascular channel system limit potential-determining ions’ access to the mineralized matrix. These linings may have an important role in mineral homeostasis and control of ion fluxes between bone compartments. Key Words: Streaming potentialsZeta (
Electrokinetic Behavior of Intact Wet Bone: Compartmental Model W. R. Walsh and N. Guzelsu Rutgers University Biomedical Engineering Department, SOM Biomechanics Program, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, U.S.A.
Summary: Streaming potential experiments were performed on chemicallytreated intact wet bone plugs equilibrated in potential-determining ion buffers. Comparison of calculated zeta (5) potentials from intact wet bone streaming potentials and bone particle electrophoresis indicates different values. Intact streaming potential experiments, where fluid is forced through the samples, represents flow, primarily through the vascular channel system, and contribution of the organically-lined channels to the electrokinetic potential. Bone particle electrophoresis represents mainly the electrokinetic contribution of exposed mineralized matrix. The organic linings present in the vascular channel system limit potential-determining ions’ access to the mineralized matrix. These linings may have an important role in mineral homeostasis and control of ion fluxes between bone compartments. Key Words: Streaming potentialsZeta (
