Accepted Article
Received Date : 13-Jun-2013 Revised Date : 27-Feb-2014 Accepted Date : 06-Mar-2014 Article type
: Randomized Clinical Trial
Efficacy of photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial
Betsy Joseph1, Chandra Sekhar Prasanth2, Baiju Kamalasanan Vijayakumari3,
Prasanthila Janam1, Narayanan Subhash2* 1
Department of Periodontics,Government Dental College, Thiruvananthapuram – 695
011, Kerala, India,
2
Biophotonics Laboratory,Centre for Earth Science Studies,
Akkulam,Thiruvananthapuram-695031,
Kerala,
India;
3
Department
of
Statistics,
Government Women’s College, Vazhuthacaud, Thiruvananthapuram - 695014, Kerala, India.
Present affiliation of Corresponding Author: Vinvish Technologies Ltd. Thejaswini Building, Technopark Park, Trivandrum - 695581, India
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/jcpe.12249 This article is protected by copyright. All rights reserved.
Accepted Article
Tel: +91-9400497015; email: [email protected]
Conflict of interest and source of funding statement The authors declare that they have no conflict of interest. This study was supported by a grant from Department of Science &Technology, Government of India.
Abstract Aim: To evaluate the potential of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of chronic periodontitis. Materials and methods: In a single-centered randomized and controlled clinical trial, 90 patients (51females and 39 males) with untreated chronic periodontitis were randomly assigned to receive SRP with aPDT (test group) or SRP alone (control group). Clinical parameters and halitosis were recorded for 6 months after treatment by a periodontist who was blinded to the procedure. Results: Intergroup and intra-group statistical analyses were performed. Significant difference between the two groups with respect to each variable was assessed using non- parametric Rank Order ANCOVA. Probing pocket depth and clinical attachment levels showed statistically significant reduction in the test group on evaluation at 3 months and 6 months as compared to the control group (p
Received Date : 13-Jun-2013 Revised Date : 27-Feb-2014 Accepted Date : 06-Mar-2014 Article type
: Randomized Clinical Trial
Efficacy of photodynamic therapy in the management of chronic periodontitis: a randomized controlled clinical trial
Betsy Joseph1, Chandra Sekhar Prasanth2, Baiju Kamalasanan Vijayakumari3,
Prasanthila Janam1, Narayanan Subhash2* 1
Department of Periodontics,Government Dental College, Thiruvananthapuram – 695
011, Kerala, India,
2
Biophotonics Laboratory,Centre for Earth Science Studies,
Akkulam,Thiruvananthapuram-695031,
Kerala,
India;
3
Department
of
Statistics,
Government Women’s College, Vazhuthacaud, Thiruvananthapuram - 695014, Kerala, India.
Present affiliation of Corresponding Author: Vinvish Technologies Ltd. Thejaswini Building, Technopark Park, Trivandrum - 695581, India
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/jcpe.12249 This article is protected by copyright. All rights reserved.
Accepted Article
Tel: +91-9400497015; email: [email protected]
Conflict of interest and source of funding statement The authors declare that they have no conflict of interest. This study was supported by a grant from Department of Science &Technology, Government of India.
Abstract Aim: To evaluate the potential of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of chronic periodontitis. Materials and methods: In a single-centered randomized and controlled clinical trial, 90 patients (51females and 39 males) with untreated chronic periodontitis were randomly assigned to receive SRP with aPDT (test group) or SRP alone (control group). Clinical parameters and halitosis were recorded for 6 months after treatment by a periodontist who was blinded to the procedure. Results: Intergroup and intra-group statistical analyses were performed. Significant difference between the two groups with respect to each variable was assessed using non- parametric Rank Order ANCOVA. Probing pocket depth and clinical attachment levels showed statistically significant reduction in the test group on evaluation at 3 months and 6 months as compared to the control group (p
