Accepted: 11 June 2017 DOI: 10.1111/jcpe.12763
RANDOMIZED CLINICAL TRIAL
Effect of periodontal therapy with systemic antimicrobials on parameters of metabolic syndrome: A randomized clinical trial Sergio Bizzarro1
| Ubele van der Velden1 | Wijnand J. Teeuw1 | Victor E. A. Gerdes2 |
Bruno G. Loos1 1 Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands 2
Department of Internal Medicine, MC Slotervaart, Amsterdam, The Netherlands Correspondence Sergio Bizzarro, Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands. Email: [email protected] Funding information This study was funded by several sources: by the authors’ institution, by an unconditional grant from Philips Oral Healthcare, by a grant from the University of Amsterdam for the focal point “Oral Infection and Inflammation” and by a grant from the Dutch Society of Periodontology (NVvP).
Abstract Aim: To investigate the effect of basic periodontal therapy (BPT) with antimicrobials (AM) on the parameters of metabolic syndrome (MetS) (waist circumference, systolic/ diastolic blood pressure [BP], HDL-cholesterol, triglycerides, glucose). Methods: One hundred and ten periodontitis patients without known comorbidities and unaware of possible MetS were randomly assigned to BPT (n = 56) or BPT+AM (n = 54) and followed for 12 months post-therapy. Number of patients with undiagnosed MetS was also determined. Results: In all patients, the periodontal condition improved; however, the BTP+AM group showed greater pocket depth reduction than the BPT group. Post-therapy, systolic BP (p
RANDOMIZED CLINICAL TRIAL
Effect of periodontal therapy with systemic antimicrobials on parameters of metabolic syndrome: A randomized clinical trial Sergio Bizzarro1
| Ubele van der Velden1 | Wijnand J. Teeuw1 | Victor E. A. Gerdes2 |
Bruno G. Loos1 1 Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands 2
Department of Internal Medicine, MC Slotervaart, Amsterdam, The Netherlands Correspondence Sergio Bizzarro, Department of Periodontology, Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands. Email: [email protected] Funding information This study was funded by several sources: by the authors’ institution, by an unconditional grant from Philips Oral Healthcare, by a grant from the University of Amsterdam for the focal point “Oral Infection and Inflammation” and by a grant from the Dutch Society of Periodontology (NVvP).
Abstract Aim: To investigate the effect of basic periodontal therapy (BPT) with antimicrobials (AM) on the parameters of metabolic syndrome (MetS) (waist circumference, systolic/ diastolic blood pressure [BP], HDL-cholesterol, triglycerides, glucose). Methods: One hundred and ten periodontitis patients without known comorbidities and unaware of possible MetS were randomly assigned to BPT (n = 56) or BPT+AM (n = 54) and followed for 12 months post-therapy. Number of patients with undiagnosed MetS was also determined. Results: In all patients, the periodontal condition improved; however, the BTP+AM group showed greater pocket depth reduction than the BPT group. Post-therapy, systolic BP (p
