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Osteoporos Int. Author manuscript; available in PMC 2017 October 01. Published in final edited form as: Osteoporos Int. 2016 October ; 27(10): 3063–3071. doi:10.1007/s00198-016-3637-0.
Effect of concomitant vitamin D deficiency or insufficiency on lumbar spine volumetric bone mineral density and trabecular bone score in primary hyperparathyroidism M. D. Walker1, I. Saeed2, J. A. Lee3, C. Zhang1, D. Hans4, T. Lang2, and S. J. Silverberg1
Author Manuscript
1Department
of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA 2Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA 3Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA 4Center of Bone Diseases, Bone and Joint Department, Lausanne University Hospital, Lausanne, Switzerland
Abstract Summary—Lower vitamin D and higher parathyroid hormone (PTH) levels are associated with higher volumetric BMD and bone strength at the lumbar spine as measured by central quantitative computed tomography in primary hyperparathyroidism (PHPT), but there are no differences in bone microarchitecture as measured by trabecular bone score (TBS).
Author Manuscript
Introduction—The purpose of this study was to evaluate the association between 25hydroxyvitamin D (25OHD) and volumetric bone mineral density (vBMD) and the TBS at the lumbar spine (LS) in PHPT. Methods—This is a cross-sectional analysis of PHPT patients with and without low 25OHD. We measured vBMD with quantitative computed tomography (cQCT) and TBS by dual-energy X-ray absorptiometry (DXA) at the LS in 52 and 88 participants, respectively.
Author Manuscript
Results—In the cQCT cohort, those with lower vitamin D (
Osteoporos Int. Author manuscript; available in PMC 2017 October 01. Published in final edited form as: Osteoporos Int. 2016 October ; 27(10): 3063–3071. doi:10.1007/s00198-016-3637-0.
Effect of concomitant vitamin D deficiency or insufficiency on lumbar spine volumetric bone mineral density and trabecular bone score in primary hyperparathyroidism M. D. Walker1, I. Saeed2, J. A. Lee3, C. Zhang1, D. Hans4, T. Lang2, and S. J. Silverberg1
Author Manuscript
1Department
of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA 2Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USA 3Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA 4Center of Bone Diseases, Bone and Joint Department, Lausanne University Hospital, Lausanne, Switzerland
Abstract Summary—Lower vitamin D and higher parathyroid hormone (PTH) levels are associated with higher volumetric BMD and bone strength at the lumbar spine as measured by central quantitative computed tomography in primary hyperparathyroidism (PHPT), but there are no differences in bone microarchitecture as measured by trabecular bone score (TBS).
Author Manuscript
Introduction—The purpose of this study was to evaluate the association between 25hydroxyvitamin D (25OHD) and volumetric bone mineral density (vBMD) and the TBS at the lumbar spine (LS) in PHPT. Methods—This is a cross-sectional analysis of PHPT patients with and without low 25OHD. We measured vBMD with quantitative computed tomography (cQCT) and TBS by dual-energy X-ray absorptiometry (DXA) at the LS in 52 and 88 participants, respectively.
Author Manuscript
Results—In the cQCT cohort, those with lower vitamin D (
