Editorial

Please find listed below “The Ten Most Highly Cited Articles” and “The Ten Most Frequently Downloaded Articles” in the Journal of Pharmaceutical Sciences (JPharmSci ) in 2013. Note that in tabulating these lists, we considered all papers published in JPharmSci , irrespective of their date of publication (i.e., 1912–2013). The journal’s Editorial Team feels that this information will be of great interest to the authors who publish their manuscripts in JPharmSci as it reflects in “citation metrics” and “usage metrics” the prevailing interests of the journal’s readers and the “long-term” impact of research results published in JPharmSci . In 2012, the impact of JPharmSci , as judged by “citation metrics,” was 3.130 for the 2-year impact factor and 3.385 for the 5-year impact factor. The 5-year impact factor, which is a better reflection of a journal’s “long-term impact” because it averages citation data over the most recent 5 years rather than the most recent 2 years, is very consistent with the “full text downloads” of papers published in JPharmSci from 1912 to 1995 and by the frequency at which older papers in JPharmSci are cited by today’s authors (see below the list of “Ten Most Highly Cited Papers in 2013”). It is equally important to mention that the journal’s impact as judged by “usage metrics” (i.e., article downloads) continued to grow in 2013. For example, in 2013, papers published in JPharmSci from 1996 to 2013 were downloaded 702,566 times from the journal’s website. This represents an 11.1% increase in the number of “full text” downloads as compared with 2012. In 2013, the papers in the “Ten Most Frequently Downloaded Articles” (see below) were downloaded from 1685 to 2939 times. In addition, it is interesting to note that papers published in JPharmSci from 1912 to 1995 were downloaded 89,613 times in 2013 from the journal’s web site. These data clearly illustrate the continued interest of pharmaceutical scientists worldwide in the older (1912–1995) papers as well as the more recent papers (1996–2013) published in JPharmSci . The 10 Most Frequently Downloaded Articles in 2013: R

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4. Boateng JS, Matthews KH, Stevens HNE, Eccleston GM. 2008. Wound healing dressings and drug delivery systems: A review. J Pharm Sci 97:2892-2923. 5. Wang W, Singh S, Zeng DL, King K, Nema S. 2007. Antibody structure, instability, and formulation. J Pharm Sci 96:1-26. 6. Yuan A, Wu J, Tang X, Zhao L, Xu F, Hu Y. 2013. Application of near-infrared dyes for tumor imaging, photothermal, and photodynamic therapies. J Pharm Sci 102:6–28. 7. Serajuddin ATM. 1999. Solid dispersion of poorly watersoluble drugs: Early promises, subsequent problems, and recent breakthroughs. J Pharm Sci 88:1058–1066. 8. Zou A, Chen Y, Huo M, Wang J, Zhang Y, Zhou J, Zhang Q. 2013. In vivo studies of octreotide-modified N-octyl-O, Ncarboxymethyl chitosan micelles loaded with doxorubicin for tumor-targeted delivery. J Pharm Sci 102:126–135. 9. Mahler HC, Friess W, Grauschopf U, Kiese S. 2009. Protein aggregation: Pathways, induction factors and analysis. J Pharm Sci 98:2909–2934. 10. Hu L, Hansen RJ. 2013. Issues, challenges, and opportunities in model-based drug development for monoclonal antibodies. J Pharm Sci 102:2898–2908.

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1. Page NA, Fung HL. 2013. Organic nitrate metabolism and action: Toward a unifying hypothesis and the future—A dedication to Professor Leslie Z. Benet. J Pharm Sci 102:3070–3081. 2. Ishikawa T, Kajimoto Y, Sun W, Nakagawa H, Inoue Y, Ikegami Y, Miyatake SI, Kuroiwa T. 2013. Role of Nrf2 in cancer photodynamic therapy: Regulation of human ABC transporter ABCG2. J Pharm Sci 102:3058–3069. 3. Benet LZ. 2013. The role of BCS (biopharmaceutics classification system) and BDDCS (biopharmaceutics drug disposition classification system) in drug development. J Pharm Sci 102:34–42.

Journal of Pharmaceutical Sciences, Vol. 103, 2961–2962 (2014)  C 2014 Wiley Periodicals, Inc. and the American Pharmacists Association

The Ten Most Highly Cited Articles in 2013:

1. Higuchi T. 1963. Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci 52:1145–1149. 2. Serajuddin ATM. 1999. Solid dispersion of poorly watersoluble drugs: Early promises, subsequent problems, and recent breakthroughs. J Pharm Sci 88:1058–1066. 3. Boateng JS, Matthews KH, Stevens HNE, Eccleston GM. 2008. Wound healing dressings and drug delivery systems: A review. J Pharm Sci 97:2892–2923. 4. Loftsson T, Brewster ME. 1996. Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization. J Pharm Sci 85:1017–1025. 5. Hancock BC, Zografi G. 1997. Characteristics and significance of the amorphous state in pharmaceutical systems. J Pharm Sci 86:1–12. 6. Higuchi T. 1961. Rate of release of medicaments from ointment bases containing drugs in suspension. J Pharm Sci 50:874–875. 7. Vishweshwar P, McMahon JA, Bis JA, Zaworotko MJ. 2006. Pharmaceutical co-crystals. J Pharm Sci 95:499– 516. 8. Chiou WL, Riegelman S. 1971. Pharmaceutical applications of solid dispersion systems. J Pharm Sci 60:1281– 1302. 9. Brouwers J, Brewster ME, Augustijns P. 2009. Supersaturating drug delivery systems: The answer to solubilitylimited oral bioavailability? J Pharm Sci 98:2549–2572.

Borchardt, JOURNAL OF PHARMACEUTICAL SCIENCES 103:2961–2962, 2014

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EDITORIAL

10. Adams ML, Lavasanifar A, Kwon GS. 2003. Amphiphilic block copolymers for drug delivery. J Pharm Sci 92:1343– 1355. Please note that you can also view these 10 “Most Accessed” (i.e., downloads) and 10 “Most Cited” papers in 2012 online by going to http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)15206017 and clicking on the “Most Accessed” link or “Most Cited” link under SPECIAL FEATURES. In addition, two new Virtual Issues of JPharmSci (i.e., Editors’ Picks and Top Downloaded Articles) are now available with free access online at http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)15206017. The Editors’ Picks virtual issues, which will be updated quarterly, will contain approximately 10 papers published in the preceding three issues that the Editors felt contained “particularly original and significant” scientific findings. The Top Downloaded Articles virtual issues, which will be updated quarterly, will contain the 10 papers published in the preceding three issues that were most frequently downloaded.

As author access to “usage metrics” is becoming as important as author access to a journal’s impact factor, I am pleased to inform you that authors of papers published in JPharmSci after August 8, 2010 are now able to access “live” the “usage metrics” for their papers. To access these data, authors need to register on http://authorservices.wiley.com/bauthor. Authors whose papers were published prior to August 8, 2010 can request this information by contacting Tammy Dunning ([email protected]). R

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Borchardt, JOURNAL OF PHARMACEUTICAL SCIENCES 103:2961–2962, 2014

Ronald T. Borchardt Editor-in-Chief Journal of Pharmaceutical Sciences Received 17 July 2014; accepted 18 July 2014 Published online 20 August 2014 in Wiley Online Library (wileyonlinelibrary.com). DOI 10.1002/jps.24109

DOI 10.1002/jps.24109

Editorial: the ten most highly cited articles.

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