www.nature.com/scientificreports
OPEN
received: 27 March 2015 accepted: 06 August 2015 Published: 08 September 2015
Early amplitude-integrated electroencephalography predicts brain injury and neurological outcome in very preterm infants Juan Song1, Falin Xu1,2, Laishuan Wang3, Liang Gao1, Jiajia Guo1, Lei Xia1, Yanhua Zhang1, Wenhao Zhou3, Xiaoyang Wang1,4 & Changlian Zhu1,2,5 Early amplitude-integrated electroencephalography (aEEG) has been widely used in term infants with brain injury to predict neurodevelopmental outcomes; however, the prognostic value of early aEEG in preterm infants is unclear. We evaluated how well early aEEG could predict brain damage and long-term neurodevelopmental outcomes in very preterm infants compared with brain imaging assessments. We found that severe aEEG abnormalities (p = 0.000) and aEEG total score
OPEN
received: 27 March 2015 accepted: 06 August 2015 Published: 08 September 2015
Early amplitude-integrated electroencephalography predicts brain injury and neurological outcome in very preterm infants Juan Song1, Falin Xu1,2, Laishuan Wang3, Liang Gao1, Jiajia Guo1, Lei Xia1, Yanhua Zhang1, Wenhao Zhou3, Xiaoyang Wang1,4 & Changlian Zhu1,2,5 Early amplitude-integrated electroencephalography (aEEG) has been widely used in term infants with brain injury to predict neurodevelopmental outcomes; however, the prognostic value of early aEEG in preterm infants is unclear. We evaluated how well early aEEG could predict brain damage and long-term neurodevelopmental outcomes in very preterm infants compared with brain imaging assessments. We found that severe aEEG abnormalities (p = 0.000) and aEEG total score
