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Quality-of-Life Before and After Laparoscopic Sleeve Gastrectomy. A Prospective Cohort Study. Vasileios Charalampakis M.D., Ph.D, Georgios Bertsias M.D., Ph.D, Vasileios Lamprou M.D, Eelco de Bree M.D., Ph.D, John Romanos M.D., Ph.D, John Melissas M.D., Ph.D., FACS

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S1550-7289(14)00194-4 http://dx.doi.org/10.1016/j.soard.2014.04.024 SOARD1990

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Surgery for Obesity and Related Diseases

Cite this article as: Vasileios Charalampakis M.D., Ph.D, Georgios Bertsias M.D., Ph.D, Vasileios Lamprou M.D, Eelco de Bree M.D., Ph.D, John Romanos M.D., Ph.D, John Melissas M.D., Ph.D., FACS, Quality-of-Life Before and After Laparoscopic Sleeve Gastrectomy. A Prospective Cohort Study., Surgery for Obesity and Related Diseases, http://dx.doi.org/10.1016/j.soard.2014.04.024 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Title: Quality-of-Life Before and After Laparoscopic Sleeve Gastrectomy. A Prospective Cohort Study. Authors: Vasileios Charalampakis, M.D., Ph.D.a, Georgios Bertsias, M.D., Ph.D.b, Vasileios Lamprou, M.D.a, Eelco de Bree, M.D., Ph.D. a, John Romanos, M.D., Ph.D.a, John Melissas, M.D., Ph.D., FACSa Departments and Institution: a

Bariatric Unit, Department of Surgical Oncology and b Rheumatology-Clinical Immunology, Heraklion University Hospital, University of Crete, Greece. Source of funding: None Corresponding author: Prof. John Melissas, M.D., Ph.D., F.A.C.S. Professor of Surgery Bariatric Unit, Heraklion University Hospital and Medical School, University of Crete 164 Erythreas Str., 71409 Heraklion, Crete, Greece. Tel: +302810392387. Fax: +302810542090. E-mail: [email protected] Short Title: Sleeve Gastrectomy and Quality of Life

Title page Title: Quality-of-Life Before and After Laparoscopic Sleeve Gastrectomy. A Prospective Cohort Study.

Short Title: Sleeve Gastrectomy and Quality of Life

ABSTRACT Background: There is a lack of adequate prospective data on quality-of-life (QOL) and its predictors in patients undergoing Laparoscopic Sleeve Gastrectomy (LSG). Objectives: The aim of this study was to assess longitudinal changes in QOL following LSG with the use of the obesity-specific Moorehead-Ardelt II questionnaire (MAII), and to identify clinical parameters associated with QOL outcome. Setting: Bariatric Unit, Academic Hospital. Methods: Morbidly obese patients consecutively admitted for LSG, over a 30-month period, were prospectively studied. QOL was assessed using the validated Greek version of the MAII questionnaire and a visual analogue scale(VAS), preoperatively and at 6, 12 and 24 months postoperatively. Anthropometric data and obesity-related co-morbidities were recorded.

Results: A total of 111 patients with a mean age 36.8±9.2 years were included. Mean preoperative body mass index (BMI) was 49.1±7.5kg/m2. Percentage excess BMI loss (%EBL) was 51.1±14.9, 64.2±17.9 and 66.4±18.0 at 6, 12 and 24 months, respectively. Postoperatively, all obesity-related comorbidities were significantly improved. MAII score increased from -0.40±1.30 preoperatively, to 1.75±0.83, 2.18±0.80 and 1.95±0.71 at 6, 12 and 24 months postoperatively (trend p

Quality of life before and after laparoscopic sleeve gastrectomy. A prospective cohort study.

There is a lack of adequate prospective data on quality-of-life (QOL) and its predictors in patients undergoing laparoscopic sleeve gastrectomy (LSG)...
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