Pediatr Nephrol DOI 10.1007/s00467-014-2845-0

ORIGINAL ARTICLE

Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections Hyung Eun Yim & Hyungshin Yim & Eun Soo Bae & Sang Uk Woo & Kee Hwan Yoo

Received: 21 January 2014 / Revised: 22 April 2014 / Accepted: 29 April 2014 # IPNA 2014

Abstract Background Early predictive biomarkers for the diagnosis and management of febrile urinary tract infections (UTIs) can be valuable diagnostic tools in children. Methods The study cohort comprised 73 pediatric patients with febrile UTIs [46 with acute pyelonephritis (APN) and 27 with lower UTIs] and 56 healthy children. Urine neutrophil gelatinase-associated lipocalin (uNGAL) and kidney injury molecule-1 (uKIM-1) levels and serum cystatin C (sCysC) levels were measured. Results The uNGAL/creatinine (Cr) and uKIM-1/Cr levels were higher in the UTI group than in the controls (P

Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections.

Early predictive biomarkers for the diagnosis and management of febrile urinary tract infections (UTIs) can be valuable diagnostic tools in children...
503KB Sizes 2 Downloads 4 Views