Epilepsy Research (2014) 108, 1352—1356

journal homepage: www.elsevier.com/locate/epilepsyres

Low vitamin D levels are common in patients with epilepsy Diane L. Teagarden a, Kimford J. Meador b,∗, David W. Loring c a

Emory Healthcare, Atlanta, GA, United States Neurology & Neurological Sciences, Stanford University, Stanford, CA, United States c Neurology & Pediatrics, Emory University, Atlanta, GA, United States b

Received 6 November 2013; received in revised form 24 May 2014; accepted 13 June 2014 Available online 6 July 2014

KEYWORDS Vitamin D; Antiepileptic drugs; Epilepsy



Summary Purpose: Vitamin D is important for bone health, and vitamin D deficiency may contribute to other disorders (e.g., autoimmune, infections, cancer, degenerative, diabetic, and vascular). Enzyme-inducing antiepileptic drugs have been particularly implicated for osteoporosis risk given their effects on vitamin D. We examined the prevalence of vitamin D deficiency in adult epilepsy patients. Methods: We conducted an observational study of consecutive epilepsy patients treated by two clinicians at the Emory University Epilepsy Center from 2008 to 2011 in order to determine the frequency of low vitamin D levels and possible differential antiepileptic drug risks. Vitamin D 25-OH levels were categorized as low (

Low vitamin D levels are common in patients with epilepsy.

Vitamin D is important for bone health, and vitamin D deficiency may contribute to other disorders (e.g., autoimmune, infections, cancer, degenerative...
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