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Do caldum channeldassiHcationsaccountfor neuronal calciumchanneldi'versity? D. Swandulla, E. Carbone and H. D. Lux D. Swandullais at the Departmentof Membrane Biophysics, Max-PlanckInstitute for Biophysical Chemistry,D-3400 GStbh&en,FRG, H. D. Lux is at the Departmentof NeurophysioloD', Max-PlanckInstitute for Psychiatry, D-8033 Planeg&, FR5, and E. Carbone is at the Department of Anatomyand HumanPhysiology, Universityof To#no, I- 10125Torino,Italy.
Calcium channels can be classified by several different criteria• It is widely agreed that at least two distinct classes of Ca2+ channels coexist on central and peripheral neurons (for a review see Ref. 1). One class of channels exhibits a low threshold of activation (100 ~M. At lower neurons21,25. concentrations (~
II illl II
I
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IIII
III
I
IIIIII I
IIH
I
Do caldum channeldassiHcationsaccountfor neuronal calciumchanneldi'versity? D. Swandulla, E. Carbone and H. D. Lux D. Swandullais at the Departmentof Membrane Biophysics, Max-PlanckInstitute for Biophysical Chemistry,D-3400 GStbh&en,FRG, H. D. Lux is at the Departmentof NeurophysioloD', Max-PlanckInstitute for Psychiatry, D-8033 Planeg&, FR5, and E. Carbone is at the Department of Anatomyand HumanPhysiology, Universityof To#no, I- 10125Torino,Italy.
Calcium channels can be classified by several different criteria• It is widely agreed that at least two distinct classes of Ca2+ channels coexist on central and peripheral neurons (for a review see Ref. 1). One class of channels exhibits a low threshold of activation (100 ~M. At lower neurons21,25. concentrations (~
