William
A. Daniel,
and David
Jr.,3’4
M.D.,
L. Bennett,6
M.B.,
ABSTRACT from
to
ages
not.
and
to
significant. Low folate of foods and suggest a higher in girls than concentrations as they with decreased plasma manufacture associated were
of
higher
vitamin either
or
demonstrates Nutr. 28:
the 363-370,
is the
primary
Growth
of puberty. Dietary trations of specific been
related
to
criteria.
The
and the growth
time spurt
tion
of
subnormal
containing cultural
Results
value
physicil
intakes nutrients
but
of
of need,
In
Family
income
did
affected
related
stages particularly a significant
the
of
correlamaturity
than
with of
folate concentrations subjects. The also tested.
effect
Nutrition
28:
APRIL
their
not
(BH).
factor
income
was
low-income taking
affect
not
families.
nonprescribed
dietary
intakes
concentrations.
The
Am.
ratings.
All
subjects
physical
were
examination
but, study
J. Clin.
judged
to
and
laboratory
be
healthy
tests
subject was assigned a sex maturity rating (SMR) according to Tanner’s (4) classification. Rating 2 represented the first visible signs of pubertal change and rating 5, for practical purposes, signified adult development. Menarche occurs predominantly at SMR 4 although many girls reach menarche at rating 3. Ratings 3 and 4 are associated with the growth spurt. Blood was obtained by venipuncture and determinations of plasma folate were obtained using the Lacto bacillus casei method. Quantities of fohate in the diets were calculated from USDA Agriculture Handbook no. 29 (5). Conversion of dietary intakes from household
measurements ‘From Alabama ham,
to mffligrams the Department in Birmingham,
Alabama
of folate
was
done
by
of Pediatrics. University of University Station, Birming-
35294.
2Supported
in
010209-02-0
The method of dietary interviews, seletion of subjects, and general plan of the study has been reported (2). Two groups of adolescents comprised the study subjects. Boys and girls voluntarily coming to a Children and Youth adolescent clinic (C & Y) represented the how-income group and girls attending a private school were from families having middle-upper of Clinical
obtained statistically
a significant
family
from
to folate
following and each
Method
Journal
were
tested
was
to maturity
incomes
change,
general,
plasma
investigations
adolescent and perhaps
intakes
TheAmerican
folate were
and
of girls
acid.
to biologic
sex
4.7%
fohic
of the
and
due
study
with maturity ratings of the of family income status was
girls,
folate
a nutrition
adolescents
plasma
Maturity
than
plasma
ratings is statistically more significant chronologic age (1-3). One part of of
boys
nutritional
not
with
dietary folate and plasma
subjects.
of folate
higher
and blood concenhave traditionally velocity
data
9.4%
characteristic
onset,
research.
of the
intakes
indirectly
of relating 1975.
of completion affect the
income.
had
pattern
groups
in
of
or high
ratings
in
families
of
nutritional
concentrations
how
dietary
utilization, of nutrients. Differing maturity of adolescent subjects, during early pubertal growth, are consideration
and
having
maturity
higher
age
age
folate
intakes are in general attributed to incomplete tables of folate content need for revision of existing standards. Plasma folate concentrations were in boys at all maturity ratings but both sexes showed decreasing became more mature. The paradox of increased dietary intake associated fohate concentration reflects increased need of fohate for cellular with adolescent growth, particularly in boys. Plasma folate
income
preparations income
of
sex
had
R.D.M.S.,
M.R.A.C.P.
of families
Boys
concentrations
G. Gaines,5
intakes
adolescents
age was
Girls
B.S.,
Dietary
healthy
in relation and
Elaine
and
part Children
by
Research and
Youth
Grant
MC-R-
Project
Grant
04-H-00027 1-04-0. 3Reprint orders to Dr. William A. Daniel, Jr., Department of Pediatrics, University of Alabama in Birmingham, University Station, Birmingham, Alabama 35294. 4Professor of Pediatrics and Director, Adolescent Unit. 6lnstructor rector, 1975,
‘Chief in Adolescent
pp.
363-370.
Nutritionist, Adolescent
C&Y Medicine,
Project no. Associate
622. Di-
Unit. Printed
in U.S.A.
363
Downloaded from https://academic.oup.com/ajcn/article-abstract/28/4/363/4716457 by University of Rhode Island user on 09 December 2018
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(race) (race) (SMR)
was
significantP
A. Daniel,
and David
Jr.,3’4
M.D.,
L. Bennett,6
M.B.,
ABSTRACT from
to
ages
not.
and
to
significant. Low folate of foods and suggest a higher in girls than concentrations as they with decreased plasma manufacture associated were
of
higher
vitamin either
or
demonstrates Nutr. 28:
the 363-370,
is the
primary
Growth
of puberty. Dietary trations of specific been
related
to
criteria.
The
and the growth
time spurt
tion
of
subnormal
containing cultural
Results
value
physicil
intakes nutrients
but
of
of need,
In
Family
income
did
affected
related
stages particularly a significant
the
of
correlamaturity
than
with of
folate concentrations subjects. The also tested.
effect
Nutrition
28:
APRIL
their
not
(BH).
factor
income
was
low-income taking
affect
not
families.
nonprescribed
dietary
intakes
concentrations.
The
Am.
ratings.
All
subjects
physical
were
examination
but, study
J. Clin.
judged
to
and
laboratory
be
healthy
tests
subject was assigned a sex maturity rating (SMR) according to Tanner’s (4) classification. Rating 2 represented the first visible signs of pubertal change and rating 5, for practical purposes, signified adult development. Menarche occurs predominantly at SMR 4 although many girls reach menarche at rating 3. Ratings 3 and 4 are associated with the growth spurt. Blood was obtained by venipuncture and determinations of plasma folate were obtained using the Lacto bacillus casei method. Quantities of fohate in the diets were calculated from USDA Agriculture Handbook no. 29 (5). Conversion of dietary intakes from household
measurements ‘From Alabama ham,
to mffligrams the Department in Birmingham,
Alabama
of folate
was
done
by
of Pediatrics. University of University Station, Birming-
35294.
2Supported
in
010209-02-0
The method of dietary interviews, seletion of subjects, and general plan of the study has been reported (2). Two groups of adolescents comprised the study subjects. Boys and girls voluntarily coming to a Children and Youth adolescent clinic (C & Y) represented the how-income group and girls attending a private school were from families having middle-upper of Clinical
obtained statistically
a significant
family
from
to folate
following and each
Method
Journal
were
tested
was
to maturity
incomes
change,
general,
plasma
investigations
adolescent and perhaps
intakes
TheAmerican
folate were
and
of girls
acid.
to biologic
sex
4.7%
fohic
of the
and
due
study
with maturity ratings of the of family income status was
girls,
folate
a nutrition
adolescents
plasma
Maturity
than
plasma
ratings is statistically more significant chronologic age (1-3). One part of of
boys
nutritional
not
with
dietary folate and plasma
subjects.
of folate
higher
and blood concenhave traditionally velocity
data
9.4%
characteristic
onset,
research.
of the
intakes
indirectly
of relating 1975.
of completion affect the
income.
had
pattern
groups
in
of
or high
ratings
in
families
of
nutritional
concentrations
how
dietary
utilization, of nutrients. Differing maturity of adolescent subjects, during early pubertal growth, are consideration
and
having
maturity
higher
age
age
folate
intakes are in general attributed to incomplete tables of folate content need for revision of existing standards. Plasma folate concentrations were in boys at all maturity ratings but both sexes showed decreasing became more mature. The paradox of increased dietary intake associated fohate concentration reflects increased need of fohate for cellular with adolescent growth, particularly in boys. Plasma folate
income
preparations income
of
sex
had
R.D.M.S.,
M.R.A.C.P.
of families
Boys
concentrations
G. Gaines,5
intakes
adolescents
age was
Girls
B.S.,
Dietary
healthy
in relation and
Elaine
and
part Children
by
Research and
Youth
Grant
MC-R-
Project
Grant
04-H-00027 1-04-0. 3Reprint orders to Dr. William A. Daniel, Jr., Department of Pediatrics, University of Alabama in Birmingham, University Station, Birmingham, Alabama 35294. 4Professor of Pediatrics and Director, Adolescent Unit. 6lnstructor rector, 1975,
‘Chief in Adolescent
pp.
363-370.
Nutritionist, Adolescent
C&Y Medicine,
Project no. Associate
622. Di-
Unit. Printed
in U.S.A.
363
Downloaded from https://academic.oup.com/ajcn/article-abstract/28/4/363/4716457 by University of Rhode Island user on 09 December 2018
Dietary intakes and plasma concentrations of folate in healthy adolescents1’2
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-
(race) (race) (SMR)
was
significantP
