HIV/AIDS - Research and Palliative Care
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ORIGINAL RESEARCH
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Determinants of virological failure among patients on highly active antiretroviral therapy in University of Gondar Referral Hospital, Northwest Ethiopia: a case–control study This article was published in the following Dove Press journal: HIV/AIDS - Research and Palliative Care 8 August 2017 Number of times this article has been viewed
Belete Bayu 1 Amare Tariku 2 Abera Balcha Bulti 3 Yohannes Ayanaw Habitu 4 Terefe Derso 2 Destaw Fetene Teshome 5 1 Wag Himra Zonal Health Department, Sekota, 2Department of Human Nutrition, Institute of Public Health, 3Department of Internal Medicine, School of Medicine, 4 Department of Reproductive Health, 5 Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
Background: Viral load monitoring is used as an important biomarker for diagnosing treatment failure in patients with HIV infection/AIDS. Ethiopia has started targeted viral load monitoring. However, factors leading to virological failure are not well understood and studied. Thus, the aim of this study was to identify the determinants of virological failure among HIV-infected patients on highly active antiretroviral therapy at the University of Gondar Referral Hospital, Northwest Ethiopia. Methods: A case–control study was conducted from May to June 2015. Cases were subjects who had already experienced virological failure; controls were those without virological failure. Data were extracted from 153 cases and 153 controls through chart review. A multivariate logistic regression analysis was carried out to identify factors associated with virological failure, and variables with a p-value
Dovepress open access to scientific and medical research
ORIGINAL RESEARCH
Open Access Full Text Article
Determinants of virological failure among patients on highly active antiretroviral therapy in University of Gondar Referral Hospital, Northwest Ethiopia: a case–control study This article was published in the following Dove Press journal: HIV/AIDS - Research and Palliative Care 8 August 2017 Number of times this article has been viewed
Belete Bayu 1 Amare Tariku 2 Abera Balcha Bulti 3 Yohannes Ayanaw Habitu 4 Terefe Derso 2 Destaw Fetene Teshome 5 1 Wag Himra Zonal Health Department, Sekota, 2Department of Human Nutrition, Institute of Public Health, 3Department of Internal Medicine, School of Medicine, 4 Department of Reproductive Health, 5 Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia
Background: Viral load monitoring is used as an important biomarker for diagnosing treatment failure in patients with HIV infection/AIDS. Ethiopia has started targeted viral load monitoring. However, factors leading to virological failure are not well understood and studied. Thus, the aim of this study was to identify the determinants of virological failure among HIV-infected patients on highly active antiretroviral therapy at the University of Gondar Referral Hospital, Northwest Ethiopia. Methods: A case–control study was conducted from May to June 2015. Cases were subjects who had already experienced virological failure; controls were those without virological failure. Data were extracted from 153 cases and 153 controls through chart review. A multivariate logistic regression analysis was carried out to identify factors associated with virological failure, and variables with a p-value
