Research Case Report/Case Series
Statistical analysis: Liu. Administrative, technical, and material support: Velez, Lam, Townsend. Study supervision: Vleugels. Conflict of Interest Disclosures: None reported. Additional Information: Dr Vleugels’s career has been supported by a Medical Dermatology Career Development Award from the Dermatology Foundation. REFERENCES 1. Ramos-Casals M, Perez-Alvarez R, Diaz-Lagares C, Cuadrado M-J, Khamashta MA; BIOGEAS Study Group. Autoimmune diseases induced by biological agents: a double-edged sword? Autoimmun Rev. 2010;9(3):188-193. 2. Ramos-Casals M, Brito-Zerón P, Soto M-J, Cuadrado M-J, Khamashta MA. Autoimmune diseases induced by TNF-targeted therapies. Best Pract Res Clin Rheumatol. 2008;22(5):847-861. 3. Klein R, Rosenbach M, Kim EJ, Kim B, Werth VP, Dunham J. Tumor necrosis factor inhibitor-associated dermatomyositis. Arch Dermatol. 2010;146(7):780-784. 4. Moustou AE, Matekovits A, Dessinioti C, Antoniou C, Sfikakis PP, Stratigos AJ. Cutaneous
Anti-TNF–Induced Dermatomyositis
side effects of anti–tumor necrosis factor biologic therapy: a clinical review. J Am Acad Dermatol. 2009;61(3):486-504. 5. Riolo G, Towheed TE. Anti–tumor necrosis factor inhibitor therapy–induced dermatomyositis and fasciitis. J Rheumatol. 2012;39(1):192-194. 6. Brunasso AM, Scocco GL, Massone C. Dermatomyositis during adalimumab therapy for rheumatoid arthritis. J Rheumatol. 2010;37(7):1549-1550. 7. Hall HA, Zimmermann B. Evolution of dermatomyositis during therapy with a tumor necrosis factor α inhibitor. Arthritis Rheum. 2006;55(6):982-984. 8. Ishikawa Y, Yukawa N, Ohmura K, et al. Etanercept-induced anti-Jo-1-antibody–positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature. Clin Rheumatol. 2010;29(5):563-566. 9. Musiał J, Undas A, Celińska-Lowenhoff M. Polymyositis associated with infliximab treatment for rheumatoid arthritis. Rheumatology (Oxford). 2003;42(12):1566-1568. 10. Urata Y, Wakai Y, Kowatari K, Nitobe T, Mizushima Y. Polymyositis associated with
infliximab treatment for rheumatoid arthritis. Mod Rheumatol. 2006;16(6):410-411. 11. Ishikawa Y, Yukawa N, Kawabata D, et al. A case of antisynthetase syndrome in a rheumatoid arthritis patient with anti-PL-12 antibody following treatment with etanercept. Clin Rheumatol. 2011;30(3):429-432. 12. Ishiguro T, Takayanagi N, Miyahara Y, Yanagisawa T, Sugita Y. Antisynthetase (anti PL-7 antibody) syndrome presenting as a skin rash and exacerbation of interstitial pneumonia during treatment for rheumatoid arthritis [in Japanese]. Nihon Kokyuki Gakkai Zasshi. 2010;48(3):240-246. 13. Martínez-Cordero E, León DE, Ortega LA. Association of polymyositis with rheumatoid arthritis. Rheumatol Int. 2001;20(3):119-123. 14. Nagashima T, Minota S. Dermatomyositis in patients with rheumatoid arthritis during adalimumab therapy [letter]. J Rheumatol. 2011;38(3):574-575. 15. Euwer RL, Sontheimer RD. Amyopathic dermatomyositis (dermatomyositis siné myositis): presentation of six new cases and review of the literature. J Am Acad Dermatol. 1991;24(6, pt 1): 959-966.
NOTABLE NOTES
Dermatology on a High Note Leonard J. Hoenig, MD; Walter H. C. Burgdorf, MD
In this world of ups and downs, songs help brighten our day. Songwriters seek to inspire us with their musical compositions and have even borrowed their lyrics from dermatology to achieve a certain effect. Thus words such as “skin” and “hair” can take on a much deeper meaning when used in song, as the following examples illustrate. Sexually transmitted disease is alluded to in the popular oldie song “Poison Ivy,” recorded by The Coasters in 1959. It warns about a girl named Ivy, nicknamed “Poison Ivy,” because she has been around men spreading a disease that “Lord’ll make you itch!!” Many of us have enjoyed the 1967 rock musical “Hair.” In the show, a long hairstyle symbolized the hippie counterculture and the antiwar movement of those times. Long hair had both negative and positive connotations. For some people it suggested an irreverent lifestyle, drug use, and sexual promiscuity. For other persons it highlighted a new way of life filled with love, peace, and freedom. In 1982, legendary stars Paul McCartney and Stevie Wonder performed a song about racial tolerance titled “Ebony and Ivory.” It speaks of 2 piano keys, ebony (black) and ivory (white), that exist side by side. The song expresses hopes that one day all people will live together in “perfect harmony.” AIDS is a devastating illness and has caused much suffering and death. And then there is the stigma associated with AIDS. In 1992, renowned singer Elton John recorded “The Last Song” in memory of Ryan White, who died of AIDS at age 18 years. It describes how an estranged father finally accepts the sexual orientation of his gay son,
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terminally ill with AIDS. In honor of those who died from AIDS, we share these lyrics: ’Cause I never thought I’d lose I only thought I’d win I never dreamed I’d feel This fire beneath my skin I can’t believe you love me I never thought you’d come I guess I misjudged love Between a father and his son In 2005, the country music group Rascal Flatts released a song titled “Skin.” It tells the story of a girl named Sarabeth who is suffering with leukemia, and she is “scared to death.” On the day of her high school prom, her hair falls out from the chemotherapy. She wonders if it would be a mistake to go. Then her boyfriend arrives wearing a baseball cap, having shaved his head in sympathy. They go to the prom, they dance, “and for a moment she isn’t scared.” Songs help to fulfill the human need to express our feelings about life’s shared experiences. Sometimes our most tender moments and deepest emotions can find their expression in song, through the language of dermatology. Author Affiliations: Private practice (Hoenig); retired (Burgdorf). Corresponding Author: Leonard J. Hoenig, MD, 601 N Flamingo Rd, Ste 201, Pembroke Pines, FL 33028 ([email protected]).
JAMA Dermatology October 2013 Volume 149, Number 10
Downloaded From: http://archderm.jamanetwork.com/ by a Rutgers University Libraries User on 06/02/2015
jamadermatology.com
Statistical analysis: Liu. Administrative, technical, and material support: Velez, Lam, Townsend. Study supervision: Vleugels. Conflict of Interest Disclosures: None reported. Additional Information: Dr Vleugels’s career has been supported by a Medical Dermatology Career Development Award from the Dermatology Foundation. REFERENCES 1. Ramos-Casals M, Perez-Alvarez R, Diaz-Lagares C, Cuadrado M-J, Khamashta MA; BIOGEAS Study Group. Autoimmune diseases induced by biological agents: a double-edged sword? Autoimmun Rev. 2010;9(3):188-193. 2. Ramos-Casals M, Brito-Zerón P, Soto M-J, Cuadrado M-J, Khamashta MA. Autoimmune diseases induced by TNF-targeted therapies. Best Pract Res Clin Rheumatol. 2008;22(5):847-861. 3. Klein R, Rosenbach M, Kim EJ, Kim B, Werth VP, Dunham J. Tumor necrosis factor inhibitor-associated dermatomyositis. Arch Dermatol. 2010;146(7):780-784. 4. Moustou AE, Matekovits A, Dessinioti C, Antoniou C, Sfikakis PP, Stratigos AJ. Cutaneous
Anti-TNF–Induced Dermatomyositis
side effects of anti–tumor necrosis factor biologic therapy: a clinical review. J Am Acad Dermatol. 2009;61(3):486-504. 5. Riolo G, Towheed TE. Anti–tumor necrosis factor inhibitor therapy–induced dermatomyositis and fasciitis. J Rheumatol. 2012;39(1):192-194. 6. Brunasso AM, Scocco GL, Massone C. Dermatomyositis during adalimumab therapy for rheumatoid arthritis. J Rheumatol. 2010;37(7):1549-1550. 7. Hall HA, Zimmermann B. Evolution of dermatomyositis during therapy with a tumor necrosis factor α inhibitor. Arthritis Rheum. 2006;55(6):982-984. 8. Ishikawa Y, Yukawa N, Ohmura K, et al. Etanercept-induced anti-Jo-1-antibody–positive polymyositis in a patient with rheumatoid arthritis: a case report and review of the literature. Clin Rheumatol. 2010;29(5):563-566. 9. Musiał J, Undas A, Celińska-Lowenhoff M. Polymyositis associated with infliximab treatment for rheumatoid arthritis. Rheumatology (Oxford). 2003;42(12):1566-1568. 10. Urata Y, Wakai Y, Kowatari K, Nitobe T, Mizushima Y. Polymyositis associated with
infliximab treatment for rheumatoid arthritis. Mod Rheumatol. 2006;16(6):410-411. 11. Ishikawa Y, Yukawa N, Kawabata D, et al. A case of antisynthetase syndrome in a rheumatoid arthritis patient with anti-PL-12 antibody following treatment with etanercept. Clin Rheumatol. 2011;30(3):429-432. 12. Ishiguro T, Takayanagi N, Miyahara Y, Yanagisawa T, Sugita Y. Antisynthetase (anti PL-7 antibody) syndrome presenting as a skin rash and exacerbation of interstitial pneumonia during treatment for rheumatoid arthritis [in Japanese]. Nihon Kokyuki Gakkai Zasshi. 2010;48(3):240-246. 13. Martínez-Cordero E, León DE, Ortega LA. Association of polymyositis with rheumatoid arthritis. Rheumatol Int. 2001;20(3):119-123. 14. Nagashima T, Minota S. Dermatomyositis in patients with rheumatoid arthritis during adalimumab therapy [letter]. J Rheumatol. 2011;38(3):574-575. 15. Euwer RL, Sontheimer RD. Amyopathic dermatomyositis (dermatomyositis siné myositis): presentation of six new cases and review of the literature. J Am Acad Dermatol. 1991;24(6, pt 1): 959-966.
NOTABLE NOTES
Dermatology on a High Note Leonard J. Hoenig, MD; Walter H. C. Burgdorf, MD
In this world of ups and downs, songs help brighten our day. Songwriters seek to inspire us with their musical compositions and have even borrowed their lyrics from dermatology to achieve a certain effect. Thus words such as “skin” and “hair” can take on a much deeper meaning when used in song, as the following examples illustrate. Sexually transmitted disease is alluded to in the popular oldie song “Poison Ivy,” recorded by The Coasters in 1959. It warns about a girl named Ivy, nicknamed “Poison Ivy,” because she has been around men spreading a disease that “Lord’ll make you itch!!” Many of us have enjoyed the 1967 rock musical “Hair.” In the show, a long hairstyle symbolized the hippie counterculture and the antiwar movement of those times. Long hair had both negative and positive connotations. For some people it suggested an irreverent lifestyle, drug use, and sexual promiscuity. For other persons it highlighted a new way of life filled with love, peace, and freedom. In 1982, legendary stars Paul McCartney and Stevie Wonder performed a song about racial tolerance titled “Ebony and Ivory.” It speaks of 2 piano keys, ebony (black) and ivory (white), that exist side by side. The song expresses hopes that one day all people will live together in “perfect harmony.” AIDS is a devastating illness and has caused much suffering and death. And then there is the stigma associated with AIDS. In 1992, renowned singer Elton John recorded “The Last Song” in memory of Ryan White, who died of AIDS at age 18 years. It describes how an estranged father finally accepts the sexual orientation of his gay son,
1208
terminally ill with AIDS. In honor of those who died from AIDS, we share these lyrics: ’Cause I never thought I’d lose I only thought I’d win I never dreamed I’d feel This fire beneath my skin I can’t believe you love me I never thought you’d come I guess I misjudged love Between a father and his son In 2005, the country music group Rascal Flatts released a song titled “Skin.” It tells the story of a girl named Sarabeth who is suffering with leukemia, and she is “scared to death.” On the day of her high school prom, her hair falls out from the chemotherapy. She wonders if it would be a mistake to go. Then her boyfriend arrives wearing a baseball cap, having shaved his head in sympathy. They go to the prom, they dance, “and for a moment she isn’t scared.” Songs help to fulfill the human need to express our feelings about life’s shared experiences. Sometimes our most tender moments and deepest emotions can find their expression in song, through the language of dermatology. Author Affiliations: Private practice (Hoenig); retired (Burgdorf). Corresponding Author: Leonard J. Hoenig, MD, 601 N Flamingo Rd, Ste 201, Pembroke Pines, FL 33028 ([email protected]).
JAMA Dermatology October 2013 Volume 149, Number 10
Downloaded From: http://archderm.jamanetwork.com/ by a Rutgers University Libraries User on 06/02/2015
jamadermatology.com
