TERATOLOGY 45:353-360 (1992)

Demographic, Reproductive, Medical, and Environmental Factors in Relation to Gastroschisis MARTHA M. WERLER, ALLEN A. MITCHELL, AND SAMUEL SHAPIRO Slone Epidemiology Unit, Boston University School of Public Health, Brookline, Massachusetts 02146

ABSTRACT To identify risk factors for gastroschisis other than drug use in pregnancy, an analysis of data collected in a case-control surveillance program of birth defects (1976-1990) was conducted. Drug use is considered in Werler et al., Teratology, 45:361-367, 1992. Maternal demographic, reproductive, and medical factors, and first trimester environmental exposures, were compared between 76 gastroschisis cases and 2,581 malformed controls. A strong inverse association was found for maternal age: relative to women 30 years or older, relative risks for 25-29,20-24, and

Demographic, reproductive, medical, and environmental factors in relation to gastroschisis.

To identify risk factors for gastroschisis other than drug use in pregnancy, an analysis of data collected in a case-control surveillance program of b...
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