Accepted Manuscript Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review Ernest Joseph Barthélemy, M.D., M.A., Marta Melis, M.D, Errol Gordon, M.D., M.D Jamie S. Ullman, Isabelle Germano, M.D. PII:
S1878-8750(15)01748-9
DOI:
10.1016/j.wneu.2015.12.044
Reference:
WNEU 3541
To appear in:
World Neurosurgery
Received Date: 19 October 2015 Revised Date:
7 December 2015
Accepted Date: 8 December 2015
Please cite this article as: Barthélemy EJ, Melis M, Gordon E, Ullman . JS, Germano I, Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review, World Neurosurgery (2016), doi: 10.1016/j.wneu.2015.12.044. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Barthélemy
ACCEPTED MANUSCRIPT World Neurosurgery
1
Revision December2015
Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review
RI PT
Ernest Joseph Barthélemy, M.D., M.A.I, Marta Melis, M.D.I, II, Errol Gordon, M.D.I, Jamie S. Ullman, M.D.III, Isabelle Germano, M.D.I*
Affiliations:
II.
Department of Neurology, University of Cagliari, Sardinia, Italy
Department of Neurosurgery, Hofstra North Shore-LIJ School of Medicine, Hempstead, NY, USA
M AN U
III.
Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA
SC
I.
TE D
Key words: brain trauma, DECRA, decompressive craniectomy, Glasgow Outcome Scale, increased intracranial pressure, severe traumatic brain injury
AC C
EP
Abbreviations: Brain Trauma Foundation (BTF), Cerebral Perfusion Pressure (CPP), Cerebrospinal Fluid (CSF), Decompressive Craniectomy Trial (DECRA), Decompressive Craniectomy (DC), Glasgow Coma Scale (GCS), Glasgow Outcome Scale (GOS), Intracranial Pressure (ICP), Non Randomized Studies (NRS), Randomized Controlled Trial (RCT), Traumatic Brain Injury (TBI), Traumatic Intracranial Hypertension (ICH)
*Corresponding Author:
Isabelle M. Germano, MD, FACS Professor Neurosurgery, Neurology, Oncological Sciences Department of Neurosurgery The Mount Sinai Medical Center 5 East 98th Street 7th Floor New York, NY 10029 T: 212-241-9638 F: 212-831-3324 E: [email protected]
Barthélemy
ACCEPTED MANUSCRIPT
2
Abstract Objective: Systematic review of the literature to evaluate the role of decompressive craniectomy (DC) after severe traumatic brain injury (TBI), comparing the first major
RI PT
randomized clinical trial on this topic (DECRA) with subsequent literature. Methods: A systematic literature search was performed from 2011 to 2015. Citations were selected using the following inclusion criteria: closed severe TBI and DC. Exclusion criteria
SC
included: majority of patients
S1878-8750(15)01748-9
DOI:
10.1016/j.wneu.2015.12.044
Reference:
WNEU 3541
To appear in:
World Neurosurgery
Received Date: 19 October 2015 Revised Date:
7 December 2015
Accepted Date: 8 December 2015
Please cite this article as: Barthélemy EJ, Melis M, Gordon E, Ullman . JS, Germano I, Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review, World Neurosurgery (2016), doi: 10.1016/j.wneu.2015.12.044. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Barthélemy
ACCEPTED MANUSCRIPT World Neurosurgery
1
Revision December2015
Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review
RI PT
Ernest Joseph Barthélemy, M.D., M.A.I, Marta Melis, M.D.I, II, Errol Gordon, M.D.I, Jamie S. Ullman, M.D.III, Isabelle Germano, M.D.I*
Affiliations:
II.
Department of Neurology, University of Cagliari, Sardinia, Italy
Department of Neurosurgery, Hofstra North Shore-LIJ School of Medicine, Hempstead, NY, USA
M AN U
III.
Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA
SC
I.
TE D
Key words: brain trauma, DECRA, decompressive craniectomy, Glasgow Outcome Scale, increased intracranial pressure, severe traumatic brain injury
AC C
EP
Abbreviations: Brain Trauma Foundation (BTF), Cerebral Perfusion Pressure (CPP), Cerebrospinal Fluid (CSF), Decompressive Craniectomy Trial (DECRA), Decompressive Craniectomy (DC), Glasgow Coma Scale (GCS), Glasgow Outcome Scale (GOS), Intracranial Pressure (ICP), Non Randomized Studies (NRS), Randomized Controlled Trial (RCT), Traumatic Brain Injury (TBI), Traumatic Intracranial Hypertension (ICH)
*Corresponding Author:
Isabelle M. Germano, MD, FACS Professor Neurosurgery, Neurology, Oncological Sciences Department of Neurosurgery The Mount Sinai Medical Center 5 East 98th Street 7th Floor New York, NY 10029 T: 212-241-9638 F: 212-831-3324 E: [email protected]
Barthélemy
ACCEPTED MANUSCRIPT
2
Abstract Objective: Systematic review of the literature to evaluate the role of decompressive craniectomy (DC) after severe traumatic brain injury (TBI), comparing the first major
RI PT
randomized clinical trial on this topic (DECRA) with subsequent literature. Methods: A systematic literature search was performed from 2011 to 2015. Citations were selected using the following inclusion criteria: closed severe TBI and DC. Exclusion criteria
SC
included: majority of patients
