Surgical Neurology International
OPEN ACCESS For entire Editorial Board visit : http://www.surgicalneurologyint.com
Editor: James I. Ausman, MD, PhD University of California, Los Angeles, CA, USA
Original Article
Decompressive craniectomy for malignant middle cerebral artery infarction: Impact on mortality and functional outcome Mohammed Azman Mohammad Raffiq, Mohammed Saffari Mohammad Haspani, Regunath Kandasamy1, Jafri Malin Abdullah1 Department of Neurosurgery, Hospital Kuala Lumpur, Kuala Lumpur, 1Department of Neurosciences, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia E‑mail: *Mohammed Azman Mohammad Raffiq ‑ [email protected]; Mohammed Saffari Mohammad Haspani ‑ [email protected]; Regunath Kandasamy ‑ [email protected]; Jafri Malin Abdullah ‑ [email protected] *Corresponding author Received: 10 November 13 Accepted: 13 May 14 Published: 26 June 14 This article may be cited as: Raffiq MM, Haspani MM, Kandasamy R, Abdullah JM. Decompressive craniectomy for malignant middle cerebral artery infarction: Impact on mortality and functional outcome. Surg Neurol Int 2014;5:102. Available FREE in open access from: http://www.surgicalneurologyint.com/text.asp?2014/5/1/102/135342 Copyright: © 2014 Raffiq MAM. This is an open‑access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract Background: Malignant middle cerebral artery (MCA) infarction is a devastating clinical entity affecting about 10% of stroke patients. Decompressive craniectomy has been found to reduce mortality rates and improve outcome in patients. Methods: A retrospective case review study was conducted to compare patients treated with medical therapy and decompressive surgery for malignant MCA infarction in Hospital Kuala Lumpur over a period of 5 years (from January 2007 to December 2012). A total of 125 patients were included in this study; 90 (72%) patients were treated with surgery, while 35 (28%) patients were treated with medical therapy. Outcome was assessed in terms of mortality rate at 30 days, Glasgow Outcome Score (GOS) on discharge, and modified Rankin scale (mRS) at 3 and 6 months. Results: Decompressive craniectomy resulted in a significant reduction in mortality rate at 30 days (P
OPEN ACCESS For entire Editorial Board visit : http://www.surgicalneurologyint.com
Editor: James I. Ausman, MD, PhD University of California, Los Angeles, CA, USA
Original Article
Decompressive craniectomy for malignant middle cerebral artery infarction: Impact on mortality and functional outcome Mohammed Azman Mohammad Raffiq, Mohammed Saffari Mohammad Haspani, Regunath Kandasamy1, Jafri Malin Abdullah1 Department of Neurosurgery, Hospital Kuala Lumpur, Kuala Lumpur, 1Department of Neurosciences, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia E‑mail: *Mohammed Azman Mohammad Raffiq ‑ [email protected]; Mohammed Saffari Mohammad Haspani ‑ [email protected]; Regunath Kandasamy ‑ [email protected]; Jafri Malin Abdullah ‑ [email protected] *Corresponding author Received: 10 November 13 Accepted: 13 May 14 Published: 26 June 14 This article may be cited as: Raffiq MM, Haspani MM, Kandasamy R, Abdullah JM. Decompressive craniectomy for malignant middle cerebral artery infarction: Impact on mortality and functional outcome. Surg Neurol Int 2014;5:102. Available FREE in open access from: http://www.surgicalneurologyint.com/text.asp?2014/5/1/102/135342 Copyright: © 2014 Raffiq MAM. This is an open‑access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract Background: Malignant middle cerebral artery (MCA) infarction is a devastating clinical entity affecting about 10% of stroke patients. Decompressive craniectomy has been found to reduce mortality rates and improve outcome in patients. Methods: A retrospective case review study was conducted to compare patients treated with medical therapy and decompressive surgery for malignant MCA infarction in Hospital Kuala Lumpur over a period of 5 years (from January 2007 to December 2012). A total of 125 patients were included in this study; 90 (72%) patients were treated with surgery, while 35 (28%) patients were treated with medical therapy. Outcome was assessed in terms of mortality rate at 30 days, Glasgow Outcome Score (GOS) on discharge, and modified Rankin scale (mRS) at 3 and 6 months. Results: Decompressive craniectomy resulted in a significant reduction in mortality rate at 30 days (P
