Pediatric Nephrology
Pediatr Nephrol (1992) 6:507-511 9 IPNA 1992
Original article Creatinine for estimation of glomerular filtration rate Stanley Hellerstein, Uri Alon, and Bradley A. Warady Department of Pediatrics, University of Missouri-Kansas City School of Medicine and Section of Pediatric Nephrology, The Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA Received November 15, 1991; received in revised form and accepted March 10, 1992
Abstract. The aim of this study was to evaluate the plasma creatinine concentration (Pfr) and creatinine clearance (Cfr) for estimation of glomerular filtration rate (GFR). Inulin clearance (Cin) was used as the reference standard for GFR. Thirty-nine concurrent Cin and CCr studies provided data for comparing Gin with the measured Ccr and with the calculated Ccr (calc-Ccr). (Calc-Ccr = k'L/Pfr, where L = height in centimeters and k is the proportionality constant.) Thirty-one children 5.3 -20.8 years of age, with Gin ranging from 2.8 to 138.8 ml/min per 1.73 m2, participated in these studies at The Children's Mercy Hosptial. The measured Ccr was 16.7___10.3 ml/min per 1.73 m2 (P
Pediatr Nephrol (1992) 6:507-511 9 IPNA 1992
Original article Creatinine for estimation of glomerular filtration rate Stanley Hellerstein, Uri Alon, and Bradley A. Warady Department of Pediatrics, University of Missouri-Kansas City School of Medicine and Section of Pediatric Nephrology, The Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA Received November 15, 1991; received in revised form and accepted March 10, 1992
Abstract. The aim of this study was to evaluate the plasma creatinine concentration (Pfr) and creatinine clearance (Cfr) for estimation of glomerular filtration rate (GFR). Inulin clearance (Cin) was used as the reference standard for GFR. Thirty-nine concurrent Cin and CCr studies provided data for comparing Gin with the measured Ccr and with the calculated Ccr (calc-Ccr). (Calc-Ccr = k'L/Pfr, where L = height in centimeters and k is the proportionality constant.) Thirty-one children 5.3 -20.8 years of age, with Gin ranging from 2.8 to 138.8 ml/min per 1.73 m2, participated in these studies at The Children's Mercy Hosptial. The measured Ccr was 16.7___10.3 ml/min per 1.73 m2 (P
