J Physiol 594.17 (2016) pp 5031–5032
5031
Erratum/Corrigendum
Expression of concern
The Journal of Physiology
With the agreement of the authors, the Editor-in-Chief and the publisher John Wiley & Sons, The Journal of Physiology is publishing four Expressions of Concern regarding articles that appeared in The Journal between 2009 and 2014. The Journal was alerted to the strong resemblance of western blots in figures in each of these four articles to blots in other figures in the same article and/or in other articles. After investigation by journal staff and experts in the field and consultation with the authors, we could not rule out the possibility that the western blots had been duplicated. All the articles involved have overlapping authorship. The similarity of the western blots raises questions about the reliability of some of the data in the four articles. The authors, the Editor-in-Chief and the publisher considered each paper separately before agreeing that publication of an Expression of Concern for each paper was necessary. The Journal has asked the corresponding authors’ institution to investigate these cases. Claudio T. De Souza, MarisaJ.S.Frederico, Gabrielle da Luz, DennysE.Cintra, Eduardo R. Ropelle, Jose R.Pauli, and Lıcio A. Velloso(2010). Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4α pathway in insulin resistant mice. J Physiol 588.12, 2239–2253. The blots used in Figure 1C and 1G for IB: IRS2 and IB: Foxo 1 respectively appear to be identical. This blot also appears to be repeated in the following articles/figures: Figure 4C labelled as IRS-1 in the article: Patr´ıcia Oliveira Prada, Jos´e Rodrigo Pauli, Eduardo Rochete Ropelle, Henrique Gottardello Zecchin, Jos´e Barreto Campello Carvalheira, L´ıcio Augusto Velloso & Mario Jos´e Abdalla Saad (2006). Selective modulation of the CAP/Cbl pathway in the adipose tissue of high fat diet treated rats. FEBS Letters 580, 4889–4894. Figures 2D and 2F labelled as Total AMPK and alpha-tubulin respectively in the article: Eduardo R. Ropelle, Jos´e R. Pauli, Karina G. Zecchin, Mirian Ueno, Cl´audio T. de Souza, Joseane Morari, Marcel C. Faria, L´ıcio A. Velloso, Mario J. A. Saad, and Jos´e B. C. Carvalheira (2007). A central role for neuronal adenosine 5 -monophosphate-activated protein kinase in cancer-induced anorexia. Endocrinology, 148(11):5220–5229. Figure 6L labelled as Total eIF4E in the article: Eduardo R. Ropelle, Jos´e R. Pauli, Maria Fernanda A. Fernandes, Silvana A. Rocco, Rodrigo M. Marin, Joseane Morari, Kellen K. Souza, Mar´ılia M. Dias, Maria C. Gomes-Marcondes, Jos´e A.R. Gontijo, Kleber G. Franchini, L´ıcio A. Velloso, Mario J.A. Saad and Jos´e B.C. Carvalheira (2008). A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight loss. Diabetes 57, 594–605. Figure 3A labelled as IKKbeta in the article: Alexandre G. Oliveira, Bruno M. Carvalho, Nat´alia Tobar, Eduardo R. Ropelle, Jos´e R. Pauli, Renata A. Bagarolli, Dioze Guadagnini, Jos´e B.C. Carvalheira and Mario J.A. Saad (2011). Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in issues of DIO Rats. Diabetes 60, 784–796. Figure 5B labelled as Akt in the article: C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
DOI: 10.1113/JP272728
5032
Erratum/Corrigendum
J Physiol 594.17
Daniela M.L. Tsukumo, Marco A. Carvalho-Filho, Jos´e B.C. Carvalheira, Patr´ıcia O. Prada, Sandro M. Hirabara, Andr´e A. ´ Jos´e Vassallo, Rui Curi, L´ıcio A. Velloso & Mario J.A. Saad (2007). Loss-of-function mutation Schenka, Eliana P. Araujo, in toll-like receptor 4 prevents diet-induced obesity and insulin Resistance. Diabetes 56, 1986–1998. Figure 4B for Akt in the article: Kelly L Calisto, Ang´elica C Camacho, Francine C Mittestainer, Bruno M Carvalho, Dioze Guadagnini, Jos´e B Carvalheira & Mario J Saad (2012). Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis. Critical Care 16:R158. The other papers on which an Expression of Concern has been issued as a result of this investigation are: Eduardo R. Ropelle, Jos´e R. Pauli, Patr´ıcia Prada, Dennys E. Cintra, Guilherme Z. Rocha, Juliana C. Moraes, Marisa J. S. Frederico, Gabrielle da Luz, Ricardo A. Pinho, Jos´e B. C. Carvalheira, Licio A. Velloso, Mario A. Saad & Cl´audio T. De Souza (2009). Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats. J Physiol, 587(10), pp 2341–2351. DOI 10.1113/jphysiol.2009.170050. Souza Pauli LS, Ropelle EC, de Souza CT, Cintra DE, da Silva AS, de Almeida Rodrigues B, de Moura LP, Marinho R, de Oliveira V, Katashima CK, Pauli JR & Ropelle ER (2014). Exercise training decreases mitogen-activated protein kinase phosphatase-3 expression and suppresses hepatic gluconeogenesis in obese mice. J Physiol, 592(6), 1325–40. DOI: 10.1113/jphysiol.2013.264002. Eduardo R. Ropelle, Jos´e R. Pauli, Dennys E. Cintra, Marisa J. S. Frederico, Ricardo A. De Pinho, L´ıcio A. Velloso & Cl´audio T. De Souza (2009). Acute exercise modulates the Foxo1/PGC-1α pathway in the liver of diet-induced obesity rats. J Physiol. 587(9):2069–76. DOI: 10.1113/jphysiol.2008.164202.
C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
5031
Erratum/Corrigendum
Expression of concern
The Journal of Physiology
With the agreement of the authors, the Editor-in-Chief and the publisher John Wiley & Sons, The Journal of Physiology is publishing four Expressions of Concern regarding articles that appeared in The Journal between 2009 and 2014. The Journal was alerted to the strong resemblance of western blots in figures in each of these four articles to blots in other figures in the same article and/or in other articles. After investigation by journal staff and experts in the field and consultation with the authors, we could not rule out the possibility that the western blots had been duplicated. All the articles involved have overlapping authorship. The similarity of the western blots raises questions about the reliability of some of the data in the four articles. The authors, the Editor-in-Chief and the publisher considered each paper separately before agreeing that publication of an Expression of Concern for each paper was necessary. The Journal has asked the corresponding authors’ institution to investigate these cases. Claudio T. De Souza, MarisaJ.S.Frederico, Gabrielle da Luz, DennysE.Cintra, Eduardo R. Ropelle, Jose R.Pauli, and Lıcio A. Velloso(2010). Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4α pathway in insulin resistant mice. J Physiol 588.12, 2239–2253. The blots used in Figure 1C and 1G for IB: IRS2 and IB: Foxo 1 respectively appear to be identical. This blot also appears to be repeated in the following articles/figures: Figure 4C labelled as IRS-1 in the article: Patr´ıcia Oliveira Prada, Jos´e Rodrigo Pauli, Eduardo Rochete Ropelle, Henrique Gottardello Zecchin, Jos´e Barreto Campello Carvalheira, L´ıcio Augusto Velloso & Mario Jos´e Abdalla Saad (2006). Selective modulation of the CAP/Cbl pathway in the adipose tissue of high fat diet treated rats. FEBS Letters 580, 4889–4894. Figures 2D and 2F labelled as Total AMPK and alpha-tubulin respectively in the article: Eduardo R. Ropelle, Jos´e R. Pauli, Karina G. Zecchin, Mirian Ueno, Cl´audio T. de Souza, Joseane Morari, Marcel C. Faria, L´ıcio A. Velloso, Mario J. A. Saad, and Jos´e B. C. Carvalheira (2007). A central role for neuronal adenosine 5 -monophosphate-activated protein kinase in cancer-induced anorexia. Endocrinology, 148(11):5220–5229. Figure 6L labelled as Total eIF4E in the article: Eduardo R. Ropelle, Jos´e R. Pauli, Maria Fernanda A. Fernandes, Silvana A. Rocco, Rodrigo M. Marin, Joseane Morari, Kellen K. Souza, Mar´ılia M. Dias, Maria C. Gomes-Marcondes, Jos´e A.R. Gontijo, Kleber G. Franchini, L´ıcio A. Velloso, Mario J.A. Saad and Jos´e B.C. Carvalheira (2008). A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet–induced weight loss. Diabetes 57, 594–605. Figure 3A labelled as IKKbeta in the article: Alexandre G. Oliveira, Bruno M. Carvalho, Nat´alia Tobar, Eduardo R. Ropelle, Jos´e R. Pauli, Renata A. Bagarolli, Dioze Guadagnini, Jos´e B.C. Carvalheira and Mario J.A. Saad (2011). Physical exercise reduces circulating lipopolysaccharide and TLR4 activation and improves insulin signaling in issues of DIO Rats. Diabetes 60, 784–796. Figure 5B labelled as Akt in the article: C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
DOI: 10.1113/JP272728
5032
Erratum/Corrigendum
J Physiol 594.17
Daniela M.L. Tsukumo, Marco A. Carvalho-Filho, Jos´e B.C. Carvalheira, Patr´ıcia O. Prada, Sandro M. Hirabara, Andr´e A. ´ Jos´e Vassallo, Rui Curi, L´ıcio A. Velloso & Mario J.A. Saad (2007). Loss-of-function mutation Schenka, Eliana P. Araujo, in toll-like receptor 4 prevents diet-induced obesity and insulin Resistance. Diabetes 56, 1986–1998. Figure 4B for Akt in the article: Kelly L Calisto, Ang´elica C Camacho, Francine C Mittestainer, Bruno M Carvalho, Dioze Guadagnini, Jos´e B Carvalheira & Mario J Saad (2012). Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis. Critical Care 16:R158. The other papers on which an Expression of Concern has been issued as a result of this investigation are: Eduardo R. Ropelle, Jos´e R. Pauli, Patr´ıcia Prada, Dennys E. Cintra, Guilherme Z. Rocha, Juliana C. Moraes, Marisa J. S. Frederico, Gabrielle da Luz, Ricardo A. Pinho, Jos´e B. C. Carvalheira, Licio A. Velloso, Mario A. Saad & Cl´audio T. De Souza (2009). Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats. J Physiol, 587(10), pp 2341–2351. DOI 10.1113/jphysiol.2009.170050. Souza Pauli LS, Ropelle EC, de Souza CT, Cintra DE, da Silva AS, de Almeida Rodrigues B, de Moura LP, Marinho R, de Oliveira V, Katashima CK, Pauli JR & Ropelle ER (2014). Exercise training decreases mitogen-activated protein kinase phosphatase-3 expression and suppresses hepatic gluconeogenesis in obese mice. J Physiol, 592(6), 1325–40. DOI: 10.1113/jphysiol.2013.264002. Eduardo R. Ropelle, Jos´e R. Pauli, Dennys E. Cintra, Marisa J. S. Frederico, Ricardo A. De Pinho, L´ıcio A. Velloso & Cl´audio T. De Souza (2009). Acute exercise modulates the Foxo1/PGC-1α pathway in the liver of diet-induced obesity rats. J Physiol. 587(9):2069–76. DOI: 10.1113/jphysiol.2008.164202.
C 2016 The Authors. The Journal of Physiology C 2016 The Physiological Society
