DOI: 10.1038/ncomms10726
Corrigendum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer Rajat Banerjee, Nickole Russo, Min Liu, Venkatesha Basrur, Emily Bellile, Nallasivam Palanisamy, Christina S. Scanlon, Elizabeth van Tubergen, Ronald C. Inglehart, Tarek Metwally, Ram-Shankar Mani, Anastasia Yocum, Mukesh K. Nyati, Rogerio M. Castilho, Sooryanarayana Varambally, Arul M. Chinnaiyan & Nisha J. D’Silva Nature Communications 5:4527 doi: 10.1038/ncomms5527 (2014); Published 31 Jul 2014; Updated 24 Feb 2016 In Fig. 4e,f of this Article, the plotted tumour volumes are incorrect due to an error in the formula used to convert length and width measurements into volume. The formula used was ((length*width)^2)*(22/7)*(1/6), and this should have read (length*(width^2))*(22/7)*(1/6). The resulting smaller tumour volumes do not change the original conclusions. The correct version of Fig. 4 appears below.
NATURE COMMUNICATIONS | 7:10726 | DOI: 10.1038/ncomms10726 | www.nature.com/naturecommunications
1
CORRIGENDUM
NATURE COMMUNICATIONS | DOI: 10.1038/ncomms10726
kDa –55
TRIP13 Flag
–40 –55
Actin
–40 pCMV6 TRIP13
c
500
pCMV6 TRIP13
400 300 200 100
*
400
* Fold change
b Number of cells (×1,000)
a
*
300 200 100 0
0 0
50
100
150
pCMV6
TRIP13
Hours
e
g
*
Percent survival
Percent migration
i
M1 M2 M3 M4 M5
2,000 1,500 1,000 500 0 0
40 30 20 10 0
10
20 30 Days
40
* P=0.0019
0 0
10
20 30 Days
40
Proliferative index
5
pCMV6 TRIP13
500 0 10
20 30 Days
1.0
40
50
*
pCMV6
0.8 0.6 TRIP13
0.4 0.2 0.0 pCMV6 TRIP13
TUNEL
25
*
100 50 5
*
20 15 10 5 0
0
0
1,000
k
150
10
50
PCNA
15
*
1,500
0
pCMV6 TRIP13
50
j
M1 M2 M3 M4 M5
2,000
50
100
H&E
TRIP13
2,500
h
150
pCMV6 TRIP13
Mitotic index
f
pCMV6
2,500
Apoptotic index
T=24 h
T=0 h
Tumour volume (mm3)
TRIP13
Tumour volume (mm3)
pCMV6
Tumour weight (g)
d
pCMV6 TRIP13
pCMV6 TRIP13
Figure 4
2
NATURE COMMUNICATIONS | 7:10726 | DOI: 10.1038/ncomms10726 | www.nature.com/naturecommunications