Sleep Breath DOI 10.1007/s11325-013-0913-5

ORIGINAL ARTICLE

Correlation of daytime sleepiness with urine metabolites in patients with obstructive sleep apnea Man-Jeong Paik & Dong-Kyu Kim & Duc-Toan Nguyen & Gwang Lee & Chae Seo Rhee & In Young Yoon & Jeong-Whun Kim

Received: 13 June 2013 / Revised: 11 September 2013 / Accepted: 11 November 2013 # Springer-Verlag Berlin Heidelberg 2014

Abstract Purpose The apnea–hypopnea index (AHI) is closely related with the severity of daytime sleepiness, but excessive daytime sleepiness (EDS) is not presented on all patients with obstructive sleep apnea (OSA). It is unclear why daytime sleepiness is not always present in OSA patients even if their sleep is disrupted from the perspective of polysomnographic findings. This study aimed to analyze the correlation between sleepiness and urine metabolites of neurotransmitters involved in the arousal system. Methods On the basis of AHI in polysomnography, 49 consecutive OSA patients were included. According to their Epworth sleepiness scale (ESS), 23 non-sleepy patients (ESS

Correlation of daytime sleepiness with urine metabolites in patients with obstructive sleep apnea.

The apnea-hypopnea index (AHI) is closely related with the severity of daytime sleepiness, but excessive daytime sleepiness (EDS) is not presented on ...
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