ONCOLOGY LETTERS 14: 1172-1178, 2017
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Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma JINGYA CHEN1, JIANHUA WANG1, XIAO CHEN1, YAOHUI WANG2, ZHONGQIU WANG1 and DAKE LI3 Departments of 1Radiology, 2Pathology and 3Gynecology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China Received June 15, 2016; Accepted March 17, 2017 DOI: 10.3892/ol.2017.6228 Abstract. The aim of the present study was to investigate the imaging characteristics of ovarian fibrothecoma. The cases of 25 female patients with pathologically confirmed ovarian fibrothecomas were retrospectively reviewed. Tumor location, size, density, signal intensity, cystic degeneration, calcification, enhancement pattern and ascites were assessed by computed tomography (CT) (n=20) and magnetic resonance imaging (MRI) (n=5). Clinical and histological features were also evaluated. The results revealed that 23 (92.0%) patients were postmenopausal, with a mean age ± standard deviation (SD) of 60.7±10.8 years old. All 25 tumors were unilateral and a thickened endometrium was observed in 7 (28.0%) patients. In total, 24 (96.0%) tumors appeared to have well‑defined boundaries, with 1 (4%) tumor exhibiting an obscure boundary. Tumors had a mean size of 9.8±5.3 cm. Solid and predominantly solid masses were found in 16 cases (64.0%), and cystic and predominantly cystic masses were found in 9 patients (36.0%). Solid regions of masses exhibited hypodensity or isodensity in 24 patients (96.0%), with 1 patient (4.0%) exhibiting hyperdensity. The mean CT value (± SD) was 44.2±12.8 HU (range, 31‑79HU) in unenhanced images. All masses exhibited isointensity or slight hypointensity on T1‑weighted imaging, and tumor parenchyma also exhibited slight hypointensity or isointensity on T2‑weighted imaging compared with the myometrium, with or without areas of patchy hyperintensity. Contrast‑enhanced CT or MRI scans were performed on 19 patients, and the solid components (94.7%) exhibited mild to moderate enhancement in 18 patients and 1 patient (5.3%)
Correspondence to: Professor Zhongqiu Wang, Department of
Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Nanjing, Jiangsu 210029, P.R. China E‑mail: [email protected] Professor Dake Li, Department of Gynecology, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Nanjing, Jiangsu 210029, P.R. China E‑mail: [email protected]
Key words: ovary, fibrothecoma, computed tomography, magnetic resonance imaging
exhibited intense enhancement. Tumor size was positively correlated with the tumor cystic degeneration (r=0.77, P
1172
Computed tomography and magnetic resonance imaging features of ovarian fibrothecoma JINGYA CHEN1, JIANHUA WANG1, XIAO CHEN1, YAOHUI WANG2, ZHONGQIU WANG1 and DAKE LI3 Departments of 1Radiology, 2Pathology and 3Gynecology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu 210029, P.R. China Received June 15, 2016; Accepted March 17, 2017 DOI: 10.3892/ol.2017.6228 Abstract. The aim of the present study was to investigate the imaging characteristics of ovarian fibrothecoma. The cases of 25 female patients with pathologically confirmed ovarian fibrothecomas were retrospectively reviewed. Tumor location, size, density, signal intensity, cystic degeneration, calcification, enhancement pattern and ascites were assessed by computed tomography (CT) (n=20) and magnetic resonance imaging (MRI) (n=5). Clinical and histological features were also evaluated. The results revealed that 23 (92.0%) patients were postmenopausal, with a mean age ± standard deviation (SD) of 60.7±10.8 years old. All 25 tumors were unilateral and a thickened endometrium was observed in 7 (28.0%) patients. In total, 24 (96.0%) tumors appeared to have well‑defined boundaries, with 1 (4%) tumor exhibiting an obscure boundary. Tumors had a mean size of 9.8±5.3 cm. Solid and predominantly solid masses were found in 16 cases (64.0%), and cystic and predominantly cystic masses were found in 9 patients (36.0%). Solid regions of masses exhibited hypodensity or isodensity in 24 patients (96.0%), with 1 patient (4.0%) exhibiting hyperdensity. The mean CT value (± SD) was 44.2±12.8 HU (range, 31‑79HU) in unenhanced images. All masses exhibited isointensity or slight hypointensity on T1‑weighted imaging, and tumor parenchyma also exhibited slight hypointensity or isointensity on T2‑weighted imaging compared with the myometrium, with or without areas of patchy hyperintensity. Contrast‑enhanced CT or MRI scans were performed on 19 patients, and the solid components (94.7%) exhibited mild to moderate enhancement in 18 patients and 1 patient (5.3%)
Correspondence to: Professor Zhongqiu Wang, Department of
Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Nanjing, Jiangsu 210029, P.R. China E‑mail: [email protected] Professor Dake Li, Department of Gynecology, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Nanjing, Jiangsu 210029, P.R. China E‑mail: [email protected]
Key words: ovary, fibrothecoma, computed tomography, magnetic resonance imaging
exhibited intense enhancement. Tumor size was positively correlated with the tumor cystic degeneration (r=0.77, P
